ADSORB: a study on the efficacy of endovascular grafting in uncomplicated acute dissection of the descending aorta

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
Jan BrunkwallP Taylor

Abstract

Acute dissection of the descending thoracic aorta carries a 30-day mortality of around 10% with best medical treatment (BMT). In addition, about 25% will develop an aneurysm during the following 4-5 years. This is the first ever randomised trial on acute dissections comparing BMT with BMT and stent grafting of the proximal tear in patients having an uncomplicated acute dissection of the descending aorta. The commonly used temporal definition of acute dissection being within 14 days of onset of symptoms is applied. A total of 61 patients will be randomised and followed at regular intervals (1, 3, 6, 12, 18, 24, 30 and 36 months) after acute dissection. Thrombosis of the false lumen, aortic enlargement and rupture are the primary end points. The study will examine whether aortic remodelling occurs after stent grafting in acute type B dissections, and its effect on aneurysm formation, rupture and re-intervention.

References

Jan 20, 1972·The New England Journal of Medicine·D C Sabiston
Sep 1, 1970·The Annals of Thoracic Surgery·P O DailyN E Shumway
May 16, 2000·Chest·I MészárosL Szép
Aug 7, 2004·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Koichi AkutsuTeruo Takano
Oct 16, 2004·The New England Journal of Medicine·Monique PrinssenUNKNOWN Dutch Randomized Endovascular Aneurysm Management (DREAM)Trial Group
Jan 30, 2007·The Annals of Thoracic Surgery·Anthony L EstreraHazim J Safi
Aug 21, 2007·Journal of the American College of Cardiology·Jong-Min SongJae-Kwan Song
Mar 21, 2008·Journal of Vascular Surgery·Michel S MakarounUNKNOWN Gore TAG Investigators
Dec 23, 2008·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·T T TsaiC A Nienaber
Dec 5, 2009·Journal of Vascular Surgery·Richard P CambriaUNKNOWN GORE TAG Investigators
Sep 15, 2010·Circulation·Santi TrimarchiUNKNOWN International Registry of Acute Aortic Dissection (IRAD) Investigators
Jul 12, 2011·Journal of Vascular Surgery·Alexander OberhuberBernd Manfred Muehling

❮ Previous
Next ❯

Citations

Mar 6, 2013·The Journal of Cardiovascular Surgery·B O'PattersonI M Loftus
Dec 10, 2013·General Thoracic and Cardiovascular Surgery·Akihiko Usui
Jan 12, 2013·Current Treatment Options in Cardiovascular Medicine·Jip L TolenaarSanti Trimarchi
Apr 17, 2013·Der Internist·C A NienaberT Chatterjee
Jan 21, 2015·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Tadashi KitamuraKagami Miyaji
Oct 9, 2012·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·S Wong, T M Mastracci
Jun 25, 2016·Expert Review of Cardiovascular Therapy·Vikalp JainRaghuveer Vallabhaneni
Nov 6, 2013·Cardiology Clinics·Jack Z LiPrashant Vaishnava
Jan 27, 2015·The Annals of Thoracic Surgery·Anthony L EstreraHazim J Safi
Nov 4, 2016·Scandinavian Cardiovascular Journal : SCJ·Truls MyrmelKristian Bartnes
Sep 18, 2013·Vascular·Laura Capoccia, Vicente Riambau
May 21, 2015·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·David C BosanquetUNKNOWN British Society of Endovascular Therapy
Apr 30, 2016·Vascular Medicine·Michol CooperMahmoud Malas
Oct 13, 2018·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Farhood SaremiMark J Cunningham
Feb 7, 2019·The Cochrane Database of Systematic Reviews·Dominic PangPaul Bachoo
Aug 12, 2017·Current Opinion in Cardiology·Akiko TanakaAnthony L Estrera
Apr 18, 2019·Ear, Nose, & Throat Journal·Ildem DeveciReyhan Surmeli
Nov 16, 2012·The Cochrane Database of Systematic Reviews·Pinar UlugJanet T Powell
Sep 26, 2015·The Cochrane Database of Systematic Reviews·Dominic PangPaul Bachoo
Apr 8, 2018·General Thoracic and Cardiovascular Surgery·Naoki MasakiUNKNOWN STANP trial investigators
Sep 24, 2015·Current Opinion in Cardiology·Rosario ParisiRossella Fattori
Oct 2, 2020·Cardiovascular and Interventional Radiology·Ajay ChavanRohit Philip Thomas
Jan 27, 2020·The Journal of Thoracic and Cardiovascular Surgery·Dongqiao XiangChuansheng Zheng
Jul 27, 2021·Journal of Cardiac Surgery·Callum HowardMohammed Idhrees

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.