Adsorption dynamics of L-glutamic acid copolymers at a heptane/water interface

Biophysical Chemistry
C J BeverungH W Blanch

Abstract

Random copolymers of glutamic acid (glu-ala, glu-leu, glu-phe, glu-tyr) were employed to investigate the relationship between side chain structure and peptide charge on adsorption behavior at an oil/water boundary. Adsorption of a series of glutamate copolymers at a heptane/water interface was examined by the dynamic pendant-drop method to determine interfacial tension. Incorporation of leucine or phenylalanine into a glutamate copolymer results in greater tension reduction than incorporation of alanine or tyrosine. These effects are amplified at pH values near the isoelectric point of glutamate, where macroscopic adsorbed films of glu-leu and glu-phe exhibit gel-like properties in response to interfacial area compression. Differences in interfacial tension behavior of glu-tyr and glu-phe indicate the importance of the tyrosine p-hydroxyl group on adsorption and aggregation at the oil/water interface.

References

Nov 1, 1977·Journal of Biomedical Materials Research·R D Bagnall
Sep 1, 1978·Journal of Biomedical Materials Research·R D BagnallP Arundel
Jan 1, 1975·Faraday Discussions of the Chemical Society·J Benjamins, J A De Feijter
Sep 1, 1986·Advances in Colloid and Interface Science·W Norde
Jun 5, 1992·Biotechnology and Bioengineering·S F MatzkeH W Blanch

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Citations

May 16, 2001·Biotechnology and Bioengineering·A HickelH W Blanch
Nov 27, 2015·Advances in Colloid and Interface Science·Eduardo GuzmánRamón G Rubio
Aug 24, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Ellen J Robertson, Geraldine L Richmond
Feb 6, 2007·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Pascaline NgweniformBashir Ahmmad

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