Adsorption of human serum albumin onto gold: a combined electrochemical and ellipsometric study

Journal of Colloid and Interface Science
Peiqing YingGang Jin

Abstract

Human serum albumin adsorption onto gold surfaces was investigated by electrochemical and ellipsometric methods. Albumin adsorption onto gold was confirmed by the change of the open circuit potential of gold and by the ellipsometric parameter variation during albumin immobilization. In both experiments the parameters reached stable values within 10-15 min. The albumin adsorption layer thickness measured with the ellipsometer was about 1.5 nm. The adsorption of albumin under applied potential was also investigated and it was found that both positive and negative applied potential promote albumin adsorption. Changes in the optical parameters of bare gold and albumin adsorbed onto gold surface under applied potential were investigated with in situ ellipsometry. The similarity and reversibility of the optical changes showed that adsorbed albumin was stable on the gold surface under the applied potential range (-200-600 mV). The cyclic voltammograms of K3Fe(CN)6 on the modified gold surface showed that albumin could partly block the oxidation and reduction reaction.

References

Jul 16, 1992·Nature·X M He, D C Carter
Sep 1, 1986·Advances in Colloid and Interface Science·W Norde
May 1, 1988·Biomaterials·R L Williams, D F Williams
Mar 1, 1985·Journal of Biomedical Materials Research·D F WilliamsR Smith
Jul 6, 2000·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·B Montdargent, D Letourneur
Nov 1, 2005·Journal of Colloid and Interface Science·S E MoultonG G Wallace

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Citations

Feb 12, 2014·Clinica Chimica Acta; International Journal of Clinical Chemistry·Mary K RobinsonW Greg Miller
Mar 5, 2011·Colloids and Surfaces. B, Biointerfaces·Hanna M KowalczyńskaRobert Kołos
Aug 10, 2007·Journal of Biomedical Materials Research. Part a·Z KertzmanS M Aouadi
Sep 9, 2015·Journal of Colloid and Interface Science·Burcu BeykalMeagan S Mauter
Aug 2, 2016·Colloids and Surfaces. B, Biointerfaces·Htwe Ei EiKoreyoshi Imamura
Nov 20, 2013·Analytical Chemistry·Jay PatelMaryanne M Collinson
Oct 26, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Tomás E Benavidez, Carlos D Garcia
Mar 7, 2008·Sensors·Dorothee GrieshaberErik Reimhult
Mar 7, 2009·Nano Letters·Elad D MentovichShachar Richter
Aug 24, 2010·ACS Applied Materials & Interfaces·Carolina DíazPatricia L Schilardi
May 10, 2020·The Journal of Physical Chemistry. B·Stefano Di LeoneWolfgang P Meier

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