PMID: 6172782Jan 1, 1981Paper

Adsorption of plasma proteins on the surface of hydrophobic polymers. Structural aspects

Polimery w medycynie
A L IordanskiĭG Kus'

Abstract

The qualitative and quantitative composition of the adsorbed protein layer is determined by thromboresistance of artificial polymer surface. The adsorption of albumine and gammaglobuline from buffer solution to the hydrofobic polymer surfaces was investigated with ESR and electron spectroscopic method. The existence of two kinds of protein covering was demonstrated: reversible and irreversible protein layer. During the nitroxyl labelled globuline adsorption the spectrum of label is due to superposition of both reversible and irreversible kinds of adsorption. It was demonstrated by the electron microscopic method that the strongly adsorbed protein layer corresponds with the denaturated protein, the reversibly adsorbed protein in contrast is native. The architecture of protein layer on polymer surface was also investigated. The comparison of structural and physiological properties of serum protein is important for the investigation of the thromboresistant materials.

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Transactions - American Society for Artificial Internal Organs
M D LelahS L Cooper
Romanian Journal of Physiology : Physiological Sciences
G PetecC Petec
Biomaterials, Medical Devices, and Artificial Organs
T DevanathanK A Young
© 2021 Meta ULC. All rights reserved