Adult acute upper respiratory tract infections in Sicily: pattern of antibiotic drug prescription in primary care

The Journal of Antimicrobial Chemotherapy
G MazzagliaA P Caputi

Abstract

We performed an observational study of the antibiotic-prescribing behaviour of Sicilian general practitioners (GPs) in managing acute upper respiratory tract infections (URTIs). Seventy-six GPs from 25 towns, representing a patient population of 96,630, participated in the study between September 1995 and May 1996. These physicians issued 2038 antibiotic treatment courses for acute upper respiratory tract infections: 792 for acute pharyngitis, 531 for acute tonsillitis, 304 for acute laryngitis and tracheitis, 268 for suppurative and non-suppurative acute otitis media, 124 for acute sinusitis and 19 for acute rhinitis. Forty-nine different antibiotics were prescribed. The most commonly used therapeutic groups were macrolides (38.6%), cephalosporins (27.1%), a combination of penicillins with beta-lactamase inhibitors (15.7%) and extended spectrum penicillins (13.5%). For each of the above diseases, except rhinitis, more than 30 different antibiotics were used. The choice of the route of administration appeared to be influenced by the age of the patients and, significantly, by a subjective clinical assessment of disease severity rather than by any consideration of epidemiological information or evidence from clinical trials. The ...Continue Reading

Citations

Nov 30, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A PantostiP Mastrantonio
May 4, 2004·International Journal of Antimicrobial Agents·Sławomir ChlabiczBarbara Pytel-Krolczuk
Aug 21, 2013·Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society·Salih MollahalilogluAhmet Akici
Feb 22, 2002·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Anna MarcheseGian Carlo Schito
May 13, 2006·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Giovanni PolimeniAchille Patrizio Caputi
May 24, 2015·The Cochrane Database of Systematic Reviews·Ludovic Reveiz, Andrés Felipe Cardona
Apr 13, 2005·Annals of Saudi Medicine·Unal AyranciAbdurrahman Kiremitci

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