Adult autoimmune enteropathy presenting initially with acquired Acrodermatitis Enteropathica: a case report

BMC Dermatology
Erina LieSteven Hoseong Yang

Abstract

Acrodermatitis enteropathica (AE) is a rare dermatitis secondary to zinc deficiency most commonly seen as an inherited disease in infants. In the last decade, increased number of reports have been published on the acquired form that presents in adulthood. Unlike its inherited counterpart, acquired AE (AAE) is often secondary to underlying pathologic or iatrogenic etiologies that interfere with nutritional absorption, such as inflammatory bowel disease or alcoholism. Various gastrointestinal pathologies have been associated with AAE, but there is currently no report on its association with adult autoimmune enteropathy (AIE), a rare gastrointestinal disorder commonly seen in infants, with limited cases reported in adults. Here we present a case in which AAE was the initial clinical manifestation in an adult patient subsequently diagnosed with AIE. A 41-year-old African American female presented to our emergency department at the Johns Hopkins Hospital with several months of progressively worsening dermatitis in the legs and acral regions, along with worsening symptoms of diarrhea, alopecia, poor oral intake, lethargy, hematochezia, peripheral edema, and weight loss. Our dermatology team was consulted given a presentation of exqui...Continue Reading

References

Aug 1, 1982·The American Journal of Dermatopathology·J R GonzalezJ L Sanchez
Oct 11, 2002·Scandinavian Journal of Gastroenterology·B CasisJ A Solís-Herruzo
Oct 18, 2002·Pediatric Dermatology·Claudia Perafán-RiverosJosé Antônio Sanches
Dec 28, 2006·Journal of the American Academy of Dermatology·Emanual MaverakisNasim Fazel
Aug 9, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Salma AkramSusan C Abraham
Jul 20, 2012·Current Gastroenterology Reports·Nicole M GentileDarrell S Pardi
Aug 23, 2012·Archives of Dermatology·James B MacdonaldDavid J DiCaudo
Jul 6, 2014·The New England Journal of Medicine·Gautam Naresh Mankaney, Kishore Vipperla
Dec 15, 2015·The Journal of Dermatology·Keiju KobayashiMasaki Shiraishi
May 26, 2016·JAAD Case Reports·Allison P WeinkleLucia Seminario-Vidal

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Citations

Jun 27, 2019·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Valerie GlutschMatthias Goebeler
Mar 16, 2019·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Valerie GlutschMatthias Goebeler

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Methods Mentioned

BETA
biopsy
gastric bypass

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