Adult BMI change and risk of Breast Cancer: National Health and Nutrition Examination Survey (NHANES) 2005-2010

Breast Cancer : the Journal of the Japanese Breast Cancer Society
Wambui G Gathirua-MwangiVictoria L Champion

Abstract

Breast cancer is the second leading cause of cancer mortality among women in the developed world. This study assessed the association between occurrence of breast cancer and body mass index (BMI) change from age 25 to age closest to breast cancer diagnosis while exploring the modifying effects of demographic variables. The National Health and Nutrition Examination Survey data were used. Women included were ≥50 years, not pregnant and without a diagnosis of any cancer but breast. The total sample included 2895 women (172 with breast cancer and 2723 controls with no breast cancer diagnosis). Multivariate logistic regression was used to estimate the OR and 95 % CIs and interaction evaluated by including an interaction term in the model. Women whose BMI increased from normal or overweight to obese compared to those who remained at a normal BMI were found to have a 2 times higher odds (OR = 2.1; 95 % CI 1.11-3.79) of developing breast cancer. No significant association was observed for women who increased to overweight. However, a more pronounced association was observed in non-Hispanic black women (OR = 6.6; 95 % CI 1.68-25.86) and a significant association observed when they increased from normal to overweight (OR = 4.2; 95 % CI 1...Continue Reading

References

Oct 1, 2004·Nutrition and Cancer·Kathy L RadimerGreta Lee Splansky
Dec 22, 2004·Journal of General Internal Medicine·Darren A DewaltMichael P Pignone
Jun 22, 2005·Seminars in Vascular Medicine·Jacob C Seidell
Jul 13, 2006·JAMA : the Journal of the American Medical Association·A Heather EliassenSusan E Hankinson
Nov 3, 2006·Breast Cancer Research and Treatment·Martha L SlatteryTim Byers
Apr 19, 2007·European Journal of Clinical Nutrition·M A Allman-FarinelliW P T James
Oct 24, 2007·Archives of Internal Medicine·Jiyoung AhnMichael F Leitzmann
May 29, 2010·The Oncologist·Kathleen Y WolinGraham A Colditz
Jul 20, 2010·Cancer Investigation·Maria Tria TironaOscar Ballester
Feb 8, 2011·Lancet·Mariel M FinucaneUNKNOWN Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Body Mass Index)
Feb 8, 2011·CA: a Cancer Journal for Clinicians·Ahmedin JemalDavid Forman
Oct 5, 2011·CA: a Cancer Journal for Clinicians·Carol DeSantisAhmedin Jemal
Jan 19, 2012·JAMA : the Journal of the American Medical Association·Katherine M FlegalCynthia L Ogden
May 2, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·M Stommel, N Osier
Jun 16, 2012·CA: a Cancer Journal for Clinicians·Rebecca SiegelElizabeth Ward
Oct 13, 2012·Frontiers in Oncology·Reiko SuzukiMasakazu Toi
Jan 22, 2013·CA: a Cancer Journal for Clinicians·Rebecca SiegelAhmedin Jemal
Apr 26, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·A AmadouP Hainaut
May 30, 2013·American Society of Clinical Oncology Educational Book·Jennifer A Ligibel, Howard D Strickler
Jul 25, 2013·British Journal of Cancer·M D K AlsakerP R Romundstad
Oct 12, 2013·CA: a Cancer Journal for Clinicians·Carol DeSantisAhmedin Jemal
Oct 29, 2013·Journal of Molecular Endocrinology·Evan R Simpson, Kristy A Brown
Oct 31, 2013·Journal of Mammary Gland Biology and Neoplasia·Linda Vona-Davis, David P Rose
Jan 1, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Pathmawathi SubramanianNora Ahmad
Feb 11, 2014·Journal of Health Care for the Poor and Underserved·Karen D LincolnDonald Lloyd
Mar 20, 2014·Sociology of Health & Illness·Isabel Fletcher
Apr 26, 2014·Health and Quality of Life Outcomes·Andreas MielckReiner Leidl
May 30, 2014·Archives of public health = Archives belges de santé publique·Mirjam P FransenMarie-Louise Essink-Bot
Jul 6, 2014·PloS One·Benjamin W DomingueJason D Boardman
Oct 3, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jennifer A LigibelClifford A Hudis
Mar 12, 2015·Journal of the National Cancer Institute·NaNa KeumEdward L Giovannucci

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Citations

May 21, 2019·American Journal of Epidemiology·Mandy GoldbergMary Beth Terry
Jan 7, 2016·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Rong-Liang ShiQing-Hai Ji
Oct 7, 2017·Digestive Diseases and Sciences·Wambui G Gathirua-MwangiThomas F Imperiale
Jul 26, 2017·Plastic and Reconstructive Surgery. Global Open·Heidi H HonW Michael Morrissey
Jun 24, 2020·International Journal of Environmental Research and Public Health·Jung Suk ParkKyoung Chun Lee

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