Adult height and all-cause and cause-specific mortality in the Japan Public Health Center-based Prospective Study (JPHC)

PloS One
Hikaru IhiraJPHC Study Group

Abstract

Adult height is determined by both genetic characteristics and environmental factors in early life. Although previous studies have suggested that adult height is associated with risk of mortality, comprehensive associations between height and all-cause and cause-specific mortality in the Japanese population are unclear. We aimed to evaluate the associations between adult height and all-cause and cause-specific mortality among Japanese men and women in a prospective cohort study. We investigated 107,794 participants (50,755 men and 57,039 women) aged 40 to 69 years who responded to the baseline questionnaire in the Japan Public Health Center-based Prospective Study. Participants were classified by quartile of adult height obtained from a self-reported questionnaire in men (<160cm, 160-163cm, 164-167cm, ≥168cm) and women (<149cm, 149-151cm, 152-155cm, ≥156cm). Hazard ratios (HR) and 95% confidence intervals (CI) for mortality from all-cause, cancer, heart disease, cerebrovascular disease, respiratory disease, and other cause mortality were calculated using Cox proportional hazards models. During follow-up, 12,320 men and 7,030 women died. Taller adult height was associated with decreased risk for mortality from cerebrovascular di...Continue Reading

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Citations

Jun 9, 2019·Journal of Physiological Anthropology·Hiroyuki TerauraKazuhiko Kotani
Jun 12, 2019·Journal of Orthopaedic Surgery and Research·Terufumi ShibataTakuaki Yamamoto
Apr 15, 2021·Journal of Biosocial Science·Y Selvamani, P Arokiasamy
Apr 13, 2021·Obesity Science & Practice·Kimmo SorjonenMichael Ingre

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