PMID: 11924932Apr 2, 2002Paper

Adult height in advanced puberty with or without gonadotropin hormone releasing hormone analog treatment

Journal of Pediatric Endocrinology & Metabolism : JPEM
A C Couto-SilvaR Brauner

Abstract

Advanced puberty is defined as the onset of puberty in girls at 8-10 years of age and in boys at 9-11 years. This study analyzes adult height in 57 children with advanced puberty to evaluate the results of treating children (9 girls and 8 boys) with gonadotropin hormone releasing hormone (GnRH) analog and the impact of advanced puberty on adult height in untreated children (31 girls and 9 boys). For treated girls, adult height predicted at the onset of treatment (151.9+/-1.7 cm) was similar to the final adult height (155.3+/-1.4 cm), but lower than target height (157.2+/-1.6 cm, p = 0.04). For untreated girls, adult height predicted at the initial evaluation (156.7+/-1 cm) was also similar to adult height (157+/-1 cm), but lower than the target height (157.6+/-1 cm, p = 0.03). The adult heights of both treated and untreated girls were similar to their target heights. For treated boys, adult height predicted at the onset of treatment (173.2+/-3.1 cm) was greater than the final adult height (164.1+/-2.1 cm, p = 0.01), which was lower than target height (170.4+/-1.2 cm, p = 0.01). For untreated boys, adult height predicted at the initial evaluation (170.8+/-2.7 cm) was similar to both the adult height (169.1+/-1.9 cm) and target h...Continue Reading

References

Mar 1, 1976·Annals of Human Biology·J M TannerL F Resele
Nov 1, 1990·The Journal of Clinical Endocrinology and Metabolism·K E OerterG B Cutler
Feb 1, 1970·Archives of Disease in Childhood·W A Marshall, J M Tanner
Dec 1, 1970·Archives of Disease in Childhood·J M TannerR H Whitehouse
Jun 1, 1969·Archives of Disease in Childhood·W A Marshall, J M Tanner
Dec 5, 1997·The Journal of Pediatrics·C Martí-Henneberg, B Vizmanos
Apr 12, 2001·Clinical Endocrinology·W ChemaitillyR Brauner

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Citations

Aug 10, 2011·Journal of Pediatric Endocrinology & Metabolism : JPEM·Somchit JaruratanasirikulHutcha Sriplung
Sep 2, 2004·Paediatric Drugs·Franco Antoniazzi, Giorgio Zamboni

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