Adult life after surviving lymphoma in childhood

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
Nicolas X von der Weid

Abstract

Almost all pediatric lymphomas are malignant, high-grade tumors. The combined incidence of Hodgkin's disease (HD) and non-Hodgkin lymphoma (NHL) reaches 10 to 12 new cases a year per million children under the age of 16 years, representing about 10% of all pediatric cancers. HD makes up to 40% and NHL 60% of pediatric lymphomas. During the last 20 years, cure rates raised dramatically so that currently over 90% of children and adolescents with HD and about 80% of those with NHL can be cured. As cure can be achieved in a large majority of patients, long-term effects and quality of life of the survivors are nowadays the principal challenges to pediatric oncologists. Like survivors from acute lymphoblastic leukemia, young adults cured from NHL may present with neurocognitive deficits, especially if treated at a young age and with cranial irradiation. Intrathecal or high-dose intravenous chemotherapy with methotrexate may induce the same problems, although in a lesser extent and severity. Large enough prospective cohort studies like the CCSS in the USA were able to show an increased risk of second malignant neoplasms, especially brain tumors in patients formerly treated with cranial irradiation. Reduced fertility can follow exposur...Continue Reading

References

Oct 26, 1979·JAMA : the Journal of the American Medical Association·R M ChapmanJ S Malpas
Mar 1, 1992·American Journal of Obstetrics and Gynecology·J ByrneJ W Meigs
Oct 1, 1990·International Journal of Radiation Oncology, Biology, Physics·T T OrtinS S Donaldson
Jan 4, 1990·The New England Journal of Medicine·J M KaldorD Assouline
Jan 14, 1988·The New England Journal of Medicine·M A TuckerS A Rosenberg
Jun 1, 1984·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M F da CunhaP G Salvador
Jun 4, 1981·The New England Journal of Medicine·S J HorningS A Rosenberg
Jul 1, 1993·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S L HancockR T Hoppe
Aug 1, 1996·Medical and Pediatric Oncology·E J MackieS M Shalet
Sep 28, 1998·Biochimica Et Biophysica Acta·C A Felix
Oct 28, 1998·Proceedings of the National Academy of Sciences of the United States of America·C A FelixT R Rebbeck
Mar 18, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M A SmithD Vena
Dec 10, 1999·Annals of Neurology·R K MulhernA Gajjar
Jun 16, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C MetayerL B Travis
Sep 22, 2000·The Journal of Clinical Endocrinology and Metabolism·C SklarL Robison
Jan 3, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·L C KremerP A Voûte
Apr 20, 2001·Journal of the National Cancer Institute·J P NegliaL L Robison
Jul 19, 2002·Annals of Oncology : Official Journal of the European Society for Medical Oncology·L C M KremerP A Voûte
Feb 5, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·N von der WeidH P Wagner
Mar 29, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Kevin C OeffingerUNKNOWN Childhood Cancer Survivor Study
Jul 25, 2003·British Journal of Haematology·Leslie L Robison, Smita Bhatia
Jan 18, 2005·Journal of Pediatric Hematology/oncology·Han-Ming Joseph Lin, Michael A Teitell
Dec 21, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Lionel M L ChowMark L Greenberg

❮ Previous
Next ❯

Citations

May 23, 2012·Journal of Assisted Reproduction and Genetics·Pascale JadoulUNKNOWN ISFP Practice Committee
Mar 24, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·E WoodwardD Stark
Oct 30, 2008·Journal of the National Cancer Institute·Catherine M CrespiBette Caan
Mar 15, 2013·Current Opinion in Otolaryngology & Head and Neck Surgery·Vincent Vander PoortenPierre Delaere
Sep 1, 2010·Radiology and Oncology·Lorna Zadravec ZaletelBerta Jereb
Feb 13, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Robert F HobbsGeorge Sgouros
Jul 14, 2011·Journal of Clinical Research in Pediatric Endocrinology·Metin DemirkayaOkan Akacı
Oct 18, 2014·Advances in Medical Sciences·Katarzyna Muszynska-RoslanMaryna Krawczuk-Rybak
Jan 18, 2012·Seminars in Pediatric Surgery·Diana L Diesen, Michael A Skinner
Apr 26, 2011·International Journal of Radiation Oncology, Biology, Physics·Laura CellaRoberto Pacelli
May 22, 2010·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·S HabererJ-J Mazeron
Mar 13, 2010·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·D C Stefan, Peter Jacobs
Feb 10, 2009·Fertility and Sterility·Dominique de ZieglerCharles Chapron
Jan 15, 2010·Pediatric Transplantation·Isabella GuzzoLuca Dello Strologo
Mar 30, 2011·International Journal of Cancer. Journal International Du Cancer·Georg BrabantMichael M Hawkins
Mar 12, 2011·British Journal of Haematology·Avi LeaderAriel Revel
Jul 6, 2014·International Journal of Radiation Biology·Ann M PeifferJudy E Brunso-Bechtold
Jul 7, 2011·Pediatric Hematology and Oncology·Azza Abdel Gawad TantawySahar Ezz-Elarab
Dec 7, 2010·Radiation Research·Elaine Ron, Alina Brenner
Feb 26, 2013·Orvosi hetilap·Zsófia JordánGábor Kovács
May 24, 2016·PloS One·Laura WengenrothUNKNOWN Swiss Paediatric Oncology Group (SPOG)
Apr 19, 2013·Scottish Medical Journal·C M Douglas, F B Macgregor
Jun 11, 2020·Leukemia & Lymphoma·Jennifer E AgrusaMonica M Gramatges
Nov 12, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Lonneke van de Poll-FranseUNKNOWN EORTC Quality of Life Group
Feb 18, 2010·Journal of Applied Clinical Medical Physics·Maria T Vlachaki, Sanath Kumar
Jan 13, 2019·The Journal of Pharmacology and Experimental Therapeutics·Carlos Rodríguez-NogalesMaría J Blanco-Prieto
Apr 23, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Rebecca FosterNina S Kadan-Lottick
Jun 27, 2021·Cancer Epidemiology·Gabriel Y C ChunLindsay A Williams
Aug 3, 2018·ACS Nano·Carlos Rodríguez-NogalesMaría J Blanco-Prieto

❮ Previous
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