Adult mammalian neurogenesis and motivated behaviors

Integrative Zoology
Claudia Jorgensen

Abstract

Adult neurogenesis continues to captivate the curiosity of the scientific community; and researchers seem to have a particular interest in identifying the functional implications of such plasticity. While the majority of research focuses on the association between adult neurogenesis and learning and memory (including spatial learning associated with hippocampal neurogenesis and olfactory discrimination associated with neurogenesis in the olfactory system), the following review will explore the link to motivated behaviors. In particular, goal-directed behaviors such as sociosexual, parental, aggressive, as well as depression- and anxiety-like behaviors and their reciprocal association to adult neurogenesis will be evaluated. The review will detail research in humans and other mammalian species. Furthermore, the potential mechanisms underlying these neurogenic alterations will be highlighted. Lastly, the review will conclude with a discussion on the functional significance of these newly generated cells in mediating goal-directed behaviors.

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Citations

Sep 27, 2018·Integrative Zoology·Mohamed Kabbaj, Zuoxin Wang
Jul 23, 2020·Frontiers in Cell and Developmental Biology·Miriam LabuschLaure Bally-Cuif
Jul 7, 2019·Brain Sciences·Claudia JorgensenTyler Barton
Aug 13, 2020·Biomolecules·Claudia Jorgensen, Zuoxin Wang
Oct 31, 2021·Reviews in the Neurosciences·Robin VisvanatharMartina Blunder

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