PMID: 11332506May 3, 2001Paper

Adult neurogenesis in natural populations

Canadian Journal of Physiology and Pharmacology
R BoonstraJ M Wojtowicz

Abstract

The dogma that the adult brain produces no new neurons has been overturned, but the critics are still asking, so what? Is adult neurogenesis a biologically relevant phenomenon, or is it perhaps harmful because it disrupts the existing neuronal circuitry? Considering that the phenomenon is evolutionarily conserved in all mammalian species examined to date and that its relevance has been well documented in non-mammalian species, it seems self-evident that neurogenesis in adult mammals must have a role. In birds, it has been established that neurogenesis varies dramatically with seasonal changes in song production. In chickadees, the learning behaviour related to finding stored food is also correlated with seasonal adult neurogenesis. Such studies are still nonexistent in mammals, but the related evidence suggests that neurogenesis does vary seasonally in hamsters and shows sexual differences in meadow voles. To promote studies on natural populations asking fundamental questions of the purpose and function of neurogenesis, we organized a Workshop on "Hippocampal Neurogenesis in Natural Populations" in Toronto in May 2000. The Workshop highlighted recent discoveries in neurogenesis from the lab, and focused on its functional conseq...Continue Reading

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Citations

Jan 16, 2007·Progress in Neurobiology·Benjamin W Lindsey, Vincent Tropepe
Jan 14, 2009·Hippocampus·Jonathan Richard EppLiisa Ann Margaret Galea
Jun 21, 2008·Hippocampus·Mark I Ransome, Ann M Turnley
Sep 21, 2011·The European Journal of Neuroscience·Anat Barnea, Vladimir Pravosudov
Apr 20, 2018·Acta Pharmacologica Sinica·Shu-Zhen ZhuZhong-Ping Feng
Feb 22, 2005·Genes, Brain, and Behavior·J M BarkerR Boonstra
Feb 1, 2005·Journal of Neural Transmission·M E GötzP Riederer
Dec 4, 2004·Reviews in the Neurosciences·Dwight C German, Amelia J Eisch

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