PMID: 8469201Apr 5, 1993Paper

Adult T cell leukaemia lymphoma in a non-aboriginal Australian woman with no apparent risk factors

The Medical Journal of Australia
M K TongS Juneja

Abstract

To present a case of adult T cell leukaemia lymphoma (ATLL) in a non-Aboriginal Australian woman with no apparent risk factor. A 43-year-old Australian woman of European descent presented with a febrile illness associated with generalised lymphadenopathy and splenomegaly. There was lymphocytosis in the peripheral blood with a T helper cell phenotype. There were also lytic bone lesions with associated hypercalcaemia. HTLV-1 antibody was detected by agglutination assay and confirmed by western blot test. After initial response to CHOP chemotherapy (cyclophosphamide, doxorubicin, vincristine, prednisolone), she relapsed and died with central nervous system involvement eight months after the initial diagnosis. To our knowledge this is only the third case of ATLL in a non-Aboriginal person in Australia.

References

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Citations

Jul 5, 1993·The Medical Journal of Australia·D ThyagarajanB S Gilligan
Jul 5, 1993·The Medical Journal of Australia·R N Heard
Mar 15, 1996·International Journal of Cancer. Journal International Du Cancer·M ChironnaS Barbuti

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