PMID: 6971703Apr 1, 1981Paper

Adult T-cell leukemia in Japan: an ultrastructural study

Cancer
M ShamotoT Zenke

Abstract

An electron microscopic study of adult T-cell leukemia, which might be a new distinct disease entity of T-cell malignancies, is presented. The most characteristic feature of adult T-cell leukemia was an extremely irregular nucleus with condensed heterochromatin in the nuclear periphery, the greater part of which was very similar to the small-cell variant form of Sézary syndrome, although some nuclei were similar to normal-appearing lymphocytes or atypical lymphoid cells with slightly indented nuclei or Sézary cells. Nuclear pockets containing tubuloreticular structures and filamentous structures etc., were also characteristic. Regarding the cytoplasmic features, the appearance of clustered dense bodies seemed to be a distinguishing feature of adult T-cell leukemia. Tubuloreticular structures were also observed in some cases. The nature of the test tube-shaped or ring-shaped forms in rough endoplasmic reticulum, which appeared in one case, is not clear.

References

Aug 1, 1979·Journal of Clinical Pathology·C S Papadimitriou, N X Papacharalampous
Sep 1, 1975·Clinical Immunology and Immunopathology·R A InselC M Balch
Dec 1, 1978·Cancer·A K SullivanB Bain
Feb 1, 1979·Cancer·S R Newcom, M E Kadin
Sep 1, 1979·Acta Pathologica Japonica·M HanaokaK Takatsuki
May 1, 1979·American Journal of Clinical Pathology·F NaeimR A Gatti
Mar 15, 1976·International Journal of Cancer. Journal International Du Cancer·H SteinG Landbeck
May 1, 1976·The Journal of Pathology·A W Helder, T M Feltkamp-Vroom
Nov 1, 1975·The Journal of Experimental Medicine·S M FuH G Kunkel
Aug 4, 1973·Lancet·D CatovskyG Stathopoulos
Oct 20, 1973·Lancet·M SumiyaJ I Yato
Aug 16, 1973·The New England Journal of Medicine·J C BrouetM Seligmann
Nov 1, 1974·Journal of Clinical Pathology·G StathopoulosE Wiltshaw

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Citations

Jan 1, 1989·Acta Neuropathologica·F Slowik, K Jellinger
Jan 1, 1984·Archives of Dermatological Research·S C van der PutteJ A van Unnik
Jan 1, 1984·Archives of Oto-rhino-laryngology·P Schenk
Jun 1, 1988·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·F BoninoA Demartini
Aug 1, 1984·Cancer Genetics and Cytogenetics·V Brito-BabapulleD Catovsky
Nov 10, 1983·The New England Journal of Medicine
May 31, 1984·The New England Journal of Medicine·T G BurrageG Miller
Mar 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·V S KalyanaramanR C Gallo
Feb 1, 1994·Pathology International·M Esumi, T Shikata
Jan 1, 1985·Ultrastructural Pathology·B Mackay
Sep 1, 1992·Ultrastructural Pathology·J G GuccionJ Zeller
Jan 1, 1991·Ultrastructural Pathology·V S VenkataseshanE Grishman
Jan 1, 1984·Journal of the American Academy of Dermatology·E J Androphy, D R Lowy
Jun 1, 1983·Journal of the American Academy of Dermatology·J CôtéD Gratton
Jul 1, 1986·Journal of Comparative Pathology·K KadotaH Nakajima
Jun 1, 1989·Human Pathology
Jan 1, 1983·Leukemia Research·G J TricotJ Jansen
Jan 1, 1988·Journal of Electron Microscopy Technique·S E Miller, D N Howell
Jan 1, 1988·Journal of Electron Microscopy Technique·J A Tucker
Nov 1, 1988·Annals of Neurology·M D CusimanoS M Cohen
Aug 15, 1984·Cancer·S H SwerdlowA G Stansfeld
Apr 15, 1983·Cancer·D HuhnP Rieber
Dec 1, 1983·Journal of Cutaneous Pathology·R E StahlS Zolla-Pazner
Jun 1, 1987·Journal of Medical Virology·T WatanabeT Shibayama
Nov 1, 1989·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Y K Shimizu, R H Purcell

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