Adult T-cell leukemia in spouses

Japanese Journal of Cancer Research : Gann
I SanadaT Shido

Abstract

A married couple who developed adult T-cell leukemia (ATL) is described. The husband presented with acute ATL and died soon after admission in spite of aggressive chemotherapy, and his wife, who is diagnosed as smoldering ATL, has been followed in the out-patient clinic. The couple had serum antibodies against human T-cell leukemia virus type I (HTLV-I) and the monoclonal integration of HTLV-I proviral DNA in their lymphocytes. The patients described represent the first reported example of ATL in a married couple.

References

Apr 1, 1988·American Journal of Hematology·S DenicH Dosik
Jan 1, 1985·Cancer·Y MiyamotoT Koga
Oct 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·Y HinumaI Miyoshi

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Citations

Jan 22, 1994·Lancet·K Yamaguchi
Mar 1, 1995·British Journal of Haematology·E MatutesD Catovsky
Nov 15, 2016·Frontiers in Microbiology·Carolina AlvarezKristien Verdonck

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