PMID: 18719810Aug 23, 2008Paper

Adult T-cell leukemia/lymphoma: report of two cases

Revista Da Sociedade Brasileira De Medicina Tropical
Ricardo Aparecido OlivoHelio Moraes-Souza

Abstract

Adult T-cell leukemia/lymphoma is a lymphoproliferative disorder of mature T lymphocytes associated with infection with human T-cell lymphotrophic virus type I (HTLV-I). Adult T-cell leukemia/lymphoma is characterized by clinical and laboratory polymorphism that allows it to be classified into four distinct subgroups: smoldering, chronic, acute and lymphomatous types. We present here two cases of adult T-cell leukemia/lymphoma, respectively in the acute and lymphomatous forms of the disease. Case 1 was a 35-year-old woman who presented abdominal distension accompanied by hepatosplenomegaly, adenomegaly, skin lesions, positivity for anti-HTLV-I antibodies and leukocytosis with the presence of flower cells. Case 2 was a 38-year-old man who was admitted with generalized lymphadenomegaly, positivity for anti-HTLV-I antibodies, hypercalcemia and osteolytic lesions. In this paper, we correlate the clinical-laboratory findings of these two cases with data in the literature.

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Citations

Feb 10, 2017·International Journal of STD & AIDS·Pedro D OliveiraAchiléa L Bittencourt
Mar 3, 2017·International Journal of Dermatology·Milton José Max Rodríguez-ZúñigaEberth Qujiano-Gomero
Aug 31, 2010·Revista Da Sociedade Brasileira De Medicina Tropical·Guilherme Manso de LimaPaulo Roberto Juliano Martins

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