Adult Wilms' tumor: A monoinstitutional experience and a review of the literature

Cancer
Monica TerenzianiFranca Fossati-Bellani

Abstract

The authors reviewed their institutional experience regarding adult patients with Wilms' tumor (WT) to assess their clinical characteristics and compliance with respect to children's treatment guidelines. A total of 17 adult patients (median age at the time of diagnosis of 17.5 years; range, 16-29 years) were referred to the study institute between 1983 and 2001 and were followed for a median of 131 months. The treatment modality was planned according to the two consecutive Italian protocols for WT that were active during the referral years. The patients were staged according to the National Wilms Tumor Study-4 (NWTS) staging system as follows: eight patients had Stage II disease, four patients had Stage III disease, and five patients had Stage IV disease. All the patients but one underwent nephrectomy, with three incomplete surgeries performed. Two patients with Stage II disease were treated elsewhere with nephrectomy only and they were admitted to the study institution at the time of disease recurrence. Anaplasia was found to be present in only one patient with Stage IV disease. The authors noted 9 cases of disease recurrence or progression occurring during treatment and 6 of these 9 patients died of their disease, with an ov...Continue Reading

References

Sep 1, 1989·International Journal of Radiation Oncology, Biology, Physics·B R Prestidge, S S Donaldson
Jun 1, 1988·Cancer·M LurieA Lurie
Apr 1, 1982·The Journal of Urology·R L ByrdG J D'Angio
Jan 1, 1995·Urologia Internationalis·K Weichert-JacobsenH Wand
Jan 15, 1995·Cancer·M U HentrichR C Hartenstein
Jan 1, 1994·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J KattanJ P Droz
Nov 20, 1997·Cancer·M OrdituraG Catalano
Dec 5, 2002·Journal of Chemotherapy·C CamciC Ozsarac

❮ Previous
Next ❯

Citations

Jan 24, 2007·Der Urologe. Ausg. A·V ZugorG E Schott
May 17, 2007·Der Urologe. Ausg. A·H ReinhardN Graf
Nov 27, 2010·International Urology and Nephrology·Romuald ZdrojowyJanusz Dembowski
Aug 26, 2011·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Jian-Jun LiHou-Jie Liang
May 10, 2011·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Gulden DinizCanan Vergin
Jan 12, 2008·Nephron. Clinical Practice·Ali Varan
Dec 15, 2010·Future Oncology·Christos KosmasNikolaos Mylonakis
Aug 3, 2011·Expert Review of Anticancer Therapy·Heidi SegersUNKNOWN SIOP-RTSG and the COG-Renal Tumour Committee
Nov 13, 2012·Urologic Oncology·Nicholas G CostW Robert Defoor
Feb 24, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Gemma GattaUNKNOWN RARECARE Working Group
Jan 26, 2007·Cancer Treatment Reviews·Andrea Ferrari, Archie Bleyer
Aug 6, 2013·Diagnostic Cytopathology·Carmen M PerrinoBrian T Collins
Aug 8, 2006·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Emmanuel MitryUNKNOWN EUROCARE Working Group
Jul 26, 2006·Journal of Pediatric Surgery·Andrea T BadilloKenneth W Liechty
Apr 26, 2005·Clinics in Laboratory Medicine·Joseph D Khoury
Jun 1, 2014·Journal of Pediatric Hematology/oncology·Nicholas G CostPaul H Noh
Nov 2, 2017·Nature Reviews. Urology·Marry M van den Heuvel-EibrinkUNKNOWN International Society of Paediatric Oncology — Renal Tumour Study Group (SIOP–RTSG)
Feb 24, 2018·World Journal of Surgical Oncology·Krzysztof RatajczykPawel Kowal
Sep 29, 2011·Virchows Archiv : an International Journal of Pathology·Jenny KarlssonDavid Gisselsson Nord
Jul 14, 2005·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Sheng-Yun LuChao-Cheng Huang
Nov 2, 2020·Bulletin du cancer·Hélène Sudour-BonnangeArnaud Verschuur
Mar 23, 2021·Annals of Medicine and Surgery·Namita BhutaniUrvashi Sharma
May 22, 2019·Clinical Genitourinary Cancer·Manon de Vries-BrillandMarine Gross-Goupil

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Harald ReinhardN Graf
International Journal of Radiation Oncology, Biology, Physics
John A KalapurakalPatrick R M Thomas
International Urology and Nephrology
Navneet KaurNeelam Wadhwa
Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Jian-Jun LiHou-Jie Liang
© 2022 Meta ULC. All rights reserved