PMID: 15379279Sep 24, 2004Paper

Advance in synthesis of ketolides, a new class of erythromycin derivatives

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
Ping-sheng LeiLu Liu

Abstract

Drug-resistance has become a challenging clinical problem. Ketolides, a new class of erythromycin derivatives, have shown promising effectiveness in killing drug-resistant bacteria. This article reviews recent development in synthesis of ketolides, with focus on the modification and synthesis of some important positions on erythromycin A cycles.

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Antimicrobial Resistance (ASM)

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