Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study

European Journal of Breast Health
Julia de Mello Ramirez MedinaAnke Bergmann

Abstract

To describe the clinical stage in women diagnosed with breast cancer and the association between clinical stage and Health-related quality of life (HRQoL). This was a cross-sectional study involving women diagnosed with breast cancer. HRQoL was assessed with European Organization for Research and Treatment of Cancer 30-Item Quality of Life Questionnaire and the Quality of Life Questionnaire Breast Cancer 23. The principal exposure was clinical stage (<IIB versus ≥IIB). Simple linear regression was performed and variables with p<0.20 were selected for the multiple linear regression. The final model was composed of statistically significant variables (p<0.05). In total, 302 women were included. The majority (58.9%) had been diagnosed with advanced stage cancer (≥IIB). Those at an advanced clinical stage had poorer role functioning (p=0.029), pain (p<0.001), and symptoms in the breast (p<0.001). Advanced clinical stage at diagnosis was found to be associated with worse health-related quality of life in breast cancer patients.

Citations

May 28, 2020·Journal of Adolescent and Young Adult Oncology·Ming LiDavid Currow
Jan 9, 2021·Breast Cancer Research and Treatment·Isabella Cristina Santos SoaresLuiz Claudio Santos Thuler
Nov 10, 2021·Journal of Comparative Effectiveness Research·Ernest LawChris Cameron

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