Advanced Lymphocyte-rich Classical Hodgkin Lymphoma Complicated with Fatal Hemophagocytic Syndrome

Internal Medicine
Satoshi IchikawaHideo Harigae

Abstract

Lymphocyte-rich classical Hodgkin lymphoma (LRCHL) is a rare subtype of Hodgkin lymphoma with a favorable prognosis, and an aggressive clinical course of LRCHL is uncommon. A 55-year-old man suffering from swelling in the left neck was diagnosed with LRCHL with extranodal lesions in the lung and bone marrow. Initially, he received standard ABVD chemotherapy; however, disease progression, accompanied by hemophagocytic syndrome (HPS), occurred during the second course of ABVD. He received two subsequent courses of intensive chemotherapy containing high-dose steroids, cyclophosphamide, and etoposide. Nevertheless, this therapy was only temporarily effective, and he died of due to an aggressive disease progression accompanied by uncontrollable HPS and severe coagulopathy.

References

Feb 1, 1990·Cancer·A I Radin
Jul 13, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Alexander Shimabukuro-VornhagenAndreas Josting
Nov 15, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D de JongUNKNOWN Groupe d'Etude des Lymphomes de l'Adulte
Jul 10, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Fanny MénardClaire Larroche
Dec 14, 2011·Hematology·Sheila Weitzman
Jun 14, 2013·BMJ Case Reports·Yoshinori MoritaNobuhito Ohno
Nov 1, 2013·Annals of Hematology·Akira HondaMineo Kurokawa
Mar 12, 2015·Blood·Alison M Schram, Nancy Berliner

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Citations

Mar 30, 2016·Annals of Hematology·M Ángeles Domínguez-MuñozJuan José Borrero
Jul 21, 2016·Digestive Diseases and Sciences·Diego Colom-SteeleDino Beduya
Jun 21, 2018·Anais Brasileiros De Dermatologia·Juliana Chaves Ruiz GuedesLuciana Wernersbach Pinto
Jan 1, 2018·Anais Brasileiros De Dermatologia·Juliana Chaves Ruiz GuedesLuciana Wernersbach Pinto

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