Advanced oxidation protein products and serum total oxidant/antioxidant status levels in rosacea

Postȩpy dermatologii i alergologii
Hilal Kaya ErdoganMuzaffer Bilgin

Abstract

Rosacea is a chronic, inflammatory dermatosis which develops due to the effect of genetic and environmental factors. To evaluate the oxidative stress in rosacea patients by measuring serum total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI) and advanced oxidation protein products (AOPP) levels in our study. Our study included rosacea patients and healthy volunteers aged between 18 and 65 years. Total antioxidant status, TOS and AOPP levels were measured and OSI was calculated. The study included 70 rosacea patients and 30 healthy volunteers as a control group. When TAS, TOS, OSI and AOPP levels were compared between rosacea and control groups, there was no difference for OSI levels; while TAS, TOS and AOPP levels were significantly higher in the rosacea group (p = 0.151, p = 0.013, p = 0.034, p = 0.017, respectively). In the rosacea group, there was no correlation between TAS, TOS, OSI and AOPP levels and disease duration. Besides there was no difference between family history, rosacea type, symptom frequency and ocular involvement and TAS, TOS, OSI and AOPP levels in the rosacea group. We observed that serum TAS, TOS and AOPP levels were significantly higher in rosacea patients, but there w...Continue Reading

Citations

Oct 4, 2020·Journal of Burn Care & Research : Official Publication of the American Burn Association·Handan MertNihat Mert
Apr 2, 2020·Journal of Cosmetic Dermatology·Dursun Turkmen
Jun 27, 2020·European Journal of Ophthalmology·Sayena JabbehdariAli R Djalilian
Jun 3, 2021·Cells·Gabriela Rapozo GuimarãesMariana Boroni

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Methods Mentioned

BETA
Assay
enzyme linked immunosorbent assay

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