Advanced Retinal Imaging and Ocular Parameters of the Rhesus Macaque Eye.

Translational Vision Science & Technology
Kira H LinAla Moshiri

Abstract

To determine the range of normal ocular biometry and perform advanced retinal imaging and functional assessment of the rhesus macaque eye. We performed ocular phenotyping on rhesus macaques at the California National Primate Research Center. This process consisted of anterior and posterior segment eye examination by ophthalmologists, advanced retinal imaging, and functional retinal electrophysiology. Full eye examinations were performed on 142 animals, consisting of pupillary light reflex, tonometry, external examination and photography, anterior slit lamp examination, and posterior segment examination by indirect ophthalmoscopy. Ages of the rhesus macaques ranged from 0.7 to 29 years (mean, 16.4 ± 7.5 years). Anterior segment measurements such as intraocular pressure (n = 142), corneal thickness (n = 84), lens thickness (n = 114), and axial length (n = 114) were acquired. Advanced retinal imaging in the form of fundus photography (n = 78), optical coherence tomography (n = 60), and quantitative autofluorescence (n = 44) was obtained. Electroretinography (n = 75) was used to assay retinal function. Quantitative analyses of the macular structure, retinal layer segmentation, and rod and cone photoreceptor electrical responses are...Continue Reading

References

Jan 1, 1990·Archives of Ophthalmology·H A QuigleyS M Drance
Nov 1, 1986·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·F E FreebergL W Sanders
Jan 1, 1985·Vision Research·H HeynenD van Norren
Oct 1, 1966·The British Journal of Ophthalmology·F C Hollows, P A Graham
Mar 1, 1996·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·R A Bush, P A Sieving
Jun 30, 2001·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·A S Vilupuru, A Glasser
Jul 11, 2001·Optometry and Vision Science : Official Publication of the American Academy of Optometry·M DubbelmanH A Weeber
Aug 11, 2001·Visual Neuroscience·J A JamisonP A Sieving
Oct 4, 2002·Journal of Glaucoma·Kwok Hei Mok, Vincent Wing-hong Lee
Oct 17, 2003·Current Eye Research·Michael D KnudtsonBarbara E K Klein
Oct 28, 2003·Investigative Ophthalmology & Visual Science·Tien Yin WongLarry D Hubbard
Jan 29, 2005·Documenta Ophthalmologica. Advances in Ophthalmology·Charlene B Y KimT Michael Nork
Jul 2, 2005·Journal of Glaucoma·Carol A Rasmussen, Paul L Kaufman
Jun 14, 2006·Archives of Ophthalmology·Ronald S Harwerth, Harry A Quigley
Apr 10, 2007·Vision Research·Ying Qiao-GriderEarl L Smith
Jul 11, 2009·Science·Ricki J ColmanRichard Weindruch
Oct 19, 2010·American Journal of Ophthalmology·Ana L LoducaMahnaz Shahidi
Oct 22, 2011·Investigative Ophthalmology & Visual Science·François DeloriR Theodore Smith
Aug 28, 2012·Documenta Ophthalmologica. Advances in Ophthalmology·M Dominik FischerStelios M Smirnakis
Jul 19, 2013·Investigative Ophthalmology & Visual Science·Jonathan P GreenbergFrançois C Delori
Sep 25, 2014·Investigative Ophthalmology & Visual Science·Nimesh B PatelRonald S Harwerth
Jan 1, 2014·Journal of Clinical Medicine·Janet R Sparrow, Tobias Duncker
Jun 14, 2015·Experimental Eye Research·Claude F Burgoyne
Nov 7, 2015·PloS One·Rahul A JonasJost B Jonas
Feb 13, 2016·Veterinary Pathology·H A Simmons
Feb 24, 2016·Investigative Ophthalmology & Visual Science·Robin SharmaJennifer J Hunter
Mar 24, 2016·Investigative Ophthalmology & Visual Science·Trevor J McGillMartha Neuringer
Mar 17, 2017·Progress in Retinal and Eye Research·Hongli YangClaude F Burgoyne
Oct 26, 2018·Documenta Ophthalmologica. Advances in Ophthalmology·Henry LiuCarol Westall
Jan 23, 2019·The Journal of Clinical Investigation·Ala MoshiriSara M Thomasy
Apr 17, 2019·Experimental Eye Research·Yao WangSandra R Montezuma
Sep 1, 2019·Progress in Retinal and Eye Research·Janet R SparrowJose Ronaldo Lima de Carvalho
Dec 25, 2019·Proceedings of the National Academy of Sciences of the United States of America·Serge PicaudJosé-Alain Sahel
Jul 15, 2020·Investigative Ophthalmology & Visual Science·Tu M TranGlenn Yiu

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