Advanced vulvar carcinoma: is it worth operating? A perioperative management protocol for radical and reconstructive surgery

Gynecologic Oncology
Francesco FanfaniGiovanni Scambia

Abstract

The aim of this study was to characterize the means whereby the results could be improved and the morbidity and side-effects minimized, of radical and extensive surgery performed together with plastic reconstruction, in the treatment of locally advanced and relapsed vulvar carcinoma. Between May 2000 and November 2004, twenty-three patients with locally advanced or relapsed vulvar carcinoma underwent major radical or extended vulvectomy, requiring reconstructive surgery. A consistent protocol for the perioperative management of these patients, including precautionary measures to reduce the rate of early complications, was introduced in the second study period (from November 2003) to verify the benefit on surgical outcome. An analysis of the medical reports showed an improvement in the median time of the postoperative course and related morbidity as a consequence of a strict application of the management protocol, with consequent decrease of early complications. Reconstructive surgery, which broadens the spectrum of available operative therapy in primary and locally recurrent vulvar cancer, is characterized by a high complication rate. The application of a strict perioperative protocol could reduce the number and the clinical im...Continue Reading

References

Aug 1, 1993·International Journal of Radiation Oncology, Biology, Physics·W J KohT W Griffin
Jul 13, 2000·International Journal of Radiation Oncology, Biology, Physics·S C HanB M Kacinski
May 1, 1994·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·D.J. Sebag-MontefioreJ.H. Shepherd
Sep 6, 2003·International Journal of Radiation Oncology, Biology, Physics·Angela KatzCharles F Levenback
Jun 12, 2004·British Journal of Plastic Surgery·R RagoowansiN Niranjan
Jan 19, 2005·Annals of Plastic Surgery·Marzia SalgarelloPasquale Alessandro Margariti

❮ Previous
Next ❯

Citations

May 4, 2012·Journal de gynécologie, obstétrique et biologie de la reproduction·S SanguinR Fauvet
Nov 15, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Mark H McComiskeyJohn H Price
May 7, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Giacomo CorradoGiorgia Garganese
Jun 27, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G GarganeseA C Testa
Jun 4, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G GarganeseA C Testa
Feb 24, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Vittoria RufiniAngela Collarino
Mar 3, 2021·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·V LancellottaL Tagliaferri
Feb 16, 2021·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G GarganeseA C Testa

❮ Previous
Next ❯

Related Concepts

Related Feeds

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Related Papers

Annals of Plastic Surgery
Marzia SalgarelloPasquale Alessandro Margariti
The Lancet Oncology
Michael Höckel, Nadja Dornhöfer
International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Katja N GaarenstroomIgnace Vergote
Best Practice & Research. Clinical Obstetrics & Gynaecology
Peter Blake
© 2022 Meta ULC. All rights reserved