Advancement of wound care from grafts to bioengineered smart skin substitutes

Progress in Biomaterials
Robin AugustineSabu Thomas

Abstract

This review gives a brief description on the skin and its essential functions, damages or injury which are common to the skin and the role of skin substitute to replace the functions of the skin soon after an injury. Skin substitutes have crucial role in the management of deep dermal and full thickness wounds. At present, there is no skin substitute in the market that can replace all the functions of skin 'and the research is still continuing for a better alternative. This review is an attempt to recollect and report the past efforts including skin grafting and recent trends like use of bioengineered smart skin substitutes in wound care. Incorporation functional moieties like antimicrobials and wound healing agents are also described.

References

Sep 1, 1987·Biomaterials·D QueenW H Reid
Jun 1, 1985·Burns, Including Thermal Injury·S D LinC C Yang
Oct 1, 1971·Physiological Reviews·R J Scheuplein, I H Blank
Dec 1, 1982·Plastic and Reconstructive Surgery·W C QuinbyC C Bondoc
Oct 8, 1998·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·A F BlackF A Auger
Jul 13, 2000·Proceedings of the National Academy of Sciences of the United States of America·J S SchechnerJ S Pober
Mar 29, 2001·Burns : Journal of the International Society for Burn Injuries·R L Sheridan, C Moreno
Jul 14, 2001·Burns : Journal of the International Society for Burn Injuries·J N Kearney
Jun 1, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Dorothy M SuppSteven T Boyce
Jul 18, 2002·Antimicrobial Agents and Chemotherapy·Pavel DibrovClaudia C Häse
Sep 7, 2002·Archives of Surgery·Wu Xiao-WuSteven E Wolf
Sep 17, 2002·The Journal of Investigative Dermatology·Vincent FalangaJan Hardin-Young
Dec 6, 2003·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Jeffrey S SchechnerJordan S Pober
Jan 8, 2004·The Journal of Investigative Dermatology·Alexander MargulisJonathan A Garlick
Jul 1, 2004·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Samantha A JonesDavid Parsons
Nov 24, 2004·Colloids and Surfaces. B, Biointerfaces·L A Smith, P X Ma
Dec 31, 2004·Proceedings of the National Academy of Sciences of the United States of America·David R EnisJeffrey S Schechner
Apr 29, 2005·Journal of the American Academy of Dermatology·Anna DrosouAndreas G Tzakis
Sep 6, 2005·Toxicological Sciences : an Official Journal of the Society of Toxicology·Shari GreenbergJonathan A Garlick
Sep 17, 2005·Journal of Materials Science. Materials in Medicine·Yanzhong ZhangZheng-Ming Huang
Apr 20, 2006·Burns : Journal of the International Society for Burn Injuries·F M WoodP Allen
Apr 22, 2006·Journal of Biomedical Materials Research. Part a·Shanta Raj BhattaraiHak Yong Kim
Jan 26, 2007·Journal of the Royal Society, Interface·Anthony D Metcalfe, Mark W J Ferguson
Apr 24, 2007·Journal of Biomedical Materials Research. Part a·Pengcheng ZhaoWeiliam Chen
May 22, 2007·Journal of Controlled Release : Official Journal of the Controlled Release Society·Hemin Nie, Chi-Hwa Wang
Aug 10, 2007·Journal of Biomedical Materials Research. Part a·H M Powell, S T Boyce
Sep 1, 2007·Advances in Skin & Wound Care·Jaimie T ShoresSubhas Gupta
Sep 22, 2007·Advanced Drug Delivery Reviews·Dehai LiangBenjamin Chu
Oct 30, 2007·Journal of Pharmaceutical Sciences·Joshua S BoatengGillian M Eccleston
Jan 29, 2008·Journal of the American Academy of Dermatology·Margaret A FonderAdam J Mamelak
Feb 24, 2009·Tissue Engineering. Part a·Heather M Powell, Steven T Boyce
Jul 1, 1995·Tissue Engineering·R LangerG Vunjak-Novakovic
Nov 10, 2009·Burns : Journal of the International Society for Burn Injuries·Vincent C van der VeenEsther Middelkoop
Jan 19, 2010·Orthodontics & Craniofacial Research·J LiuJ W Von den Hoff
Mar 20, 2010·Burns : Journal of the International Society for Burn Injuries·T L KhooA A Dorai
Jul 3, 2010·Plastic and Reconstructive Surgery·Nicole LindenblattMaurizio Calcagni
Feb 16, 2011·Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India·Ahmad Sukari HalimShah Jumaat Mohd Yussof
Mar 16, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Krishna R RaghupathiAdhar C Manna

❮ Previous
Next ❯

Citations

May 29, 2018·The International Journal of Artificial Organs·Tarek M SalehHeung-Myong Woo
Nov 6, 2018·Journal of Materials Science. Materials in Medicine·Robin AugustineSabu Thomas
Sep 29, 2018·The Journal of Dermatological Treatment·Christina DaiAmor Khachemoune
Feb 28, 2015·Advanced Healthcare Materials·Mohammad NorouziMasoud Soleimani
Feb 16, 2017·Phytotherapy Research : PTR·Urmimala DasKrishna Pramanik
Aug 17, 2020·Biomolecules·Shima Tavakoli, Agnes S Klar
Aug 23, 2020·International Journal of Molecular Sciences·Abdulaziz Ali AlghamdiTaieb Aouak
Dec 2, 2020·Materials Science & Engineering. C, Materials for Biological Applications·Robin AugustineAla-Eddin Al Moustafa
Jan 17, 2020·Journal of Ethnopharmacology·Nasser EbrahimpourMehrzad Mehrbani
Feb 12, 2021·Biomedical Materials·Laura Mihaela StefanOana Craciunescu
Mar 20, 2021·Journal of Tissue Engineering·Mahsa Nouri BarkestaniSara Shamdani
Mar 31, 2021·Journal of Controlled Release : Official Journal of the Controlled Release Society·Andrea LuraghiLorenzo Moroni
May 6, 2021·Macromolecular Bioscience·Matin RostamitabarSamaneh Ghazanfari
Jul 3, 2021·Ultrasound in Medicine & Biology·Yash MantriJesse V Jokerst
Jul 3, 2021·Regenerative Biomaterials·Athanasios S ArampatzisAndreana N Assimopoulou
Jul 13, 2021·Advanced Materials·Mahshid KharazihaNasim Annabi
Dec 16, 2020·ACS Biomaterials Science & Engineering·Robin AugustineJessiya Jacob

❮ Previous
Next ❯

Methods Mentioned

BETA
xenograft
xenografts
transfection

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
W H EaglsteinK Laszlo
The International Journal of Lower Extremity Wounds
P Shakespeare
Critical Care Clinics
B M Achauer, S E Martinez
© 2022 Meta ULC. All rights reserved