Advances and Prospects of Phenolic Acids Production, Biorefinery and Analysis.

Biomolecules
Egle ValancieneNaglis Malys

Abstract

Biotechnological production of phenolic acids is attracting increased interest due to their superior antioxidant activity, as well as other antimicrobial, dietary, and health benefits. As secondary metabolites, primarily found in plants and fungi, they are effective free radical scavengers due to the phenolic group available in their structure. Therefore, phenolic acids are widely utilised by pharmaceutical, food, cosmetic, and chemical industries. A demand for phenolic acids is mostly satisfied by utilising chemically synthesised compounds, with only a low quantity obtained from natural sources. As an alternative to chemical synthesis, environmentally friendly bio-based technologies are necessary for development in large-scale production. One of the most promising sustainable technologies is the utilisation of microbial cell factories for biosynthesis of phenolic acids. In this paper, we perform a systematic comparison of the best known natural sources of phenolic acids. The advances and prospects in the development of microbial cell factories for biosynthesis of these bioactive compounds are discussed in more detail. A special consideration is given to the modern production methods and analytics of phenolic acids.

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Citations

Dec 3, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Iva ŠikutenDarko Preiner
Apr 4, 2021·Journal of Fungi·Karen P Quintero-CabelloJ Fernando Ayala-Zavala
Apr 1, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Giulia Di Dalmazi, Cesidio Giuliani
Apr 24, 2021·Frontiers in Plant Science·Chaiwat AneklaphakijTakayuki Tohge
May 1, 2021·Biomolecules·Samir Meramo-HurtadoÁngel Dario Gonzalez-Delgado
May 17, 2021·Food Research International·Danilo Escobar-AvelloAnna Vallverdú-Queralt

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Methods Mentioned

BETA
electrophoresis
nuclear magnetic resonance
biosensor
biosensors

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