Advances and surgical considerations in the treatment of moyamoya disease

Eric J AriasGregory J Zipfel


Moyamoya is a rare disorder that involves steno-occlusive arterial changes of the anterior circulation, along with proliferative development of basal arterial collaterals. It is either idiopathic (called moyamoya disease) or the result of a specific underlying condition such as atherosclerosis, radiation therapy, or sickle cell disease (called moyamoya syndrome or phenomenon). In recent years, numerous insights into and advances in the understanding, evaluation, and management of moyamoya patients have occurred. This article briefly reviews the spectrum of moyamoya conditions and then provides a synopsis of numerous recent investigations that shed light on various aspects of the disease, including its clinical characteristics, natural history, underlying pathology, imaging, surgical techniques, and long-term patient outcome.

Associated Clinical Trials


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Mar 27, 2016·International Journal of Surgery Case Reports·Xuhui LiP Zichu Yang
Mar 17, 2015·Clínica e investigación en arteriosclerosis : publicación oficial de la Sociedad Española de Arteriosclerosis·Pedro ArmarioPere Cardona
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Dec 1, 2018·Journal of Neurosurgery·Kristine RavinaJonathan J Russin
Sep 10, 2018·Journal of Neurology·Amanda KahnMandip S Dhamoon
May 12, 2019·Neurosurgery·Xiaofeng DengJizong Zhao
Jun 14, 2018·Journal of Medical Case Reports·Abdelhafid HoubaMustapha Bensghir
Jul 28, 2020·Neurosurgery·Ephraim W ChurchGary K Steinberg
Nov 12, 2020·Curēus·Julie Mayeku, Miguel A Lopez-Gonzalez
Mar 12, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Harishchandra Lalgudi SrinivasanJonathan Roth

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