Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insect stings

The Journal of Allergy and Clinical Immunology
Scott H Sicherer, Donald Y m Leung

Abstract

This review highlights some of the research advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insect venom that were reported primarily in the Journal of Allergy and Clinical Immunology from 2002 through 2003. Among the topics highlighted are new insights into the pathogenesis of atopic dermatitis and potential strategies for more effective treatment of the atopic march. Patients should remain supine with raised legs during anaphylactic shock because upper body elevation could result in sudden death from loss of venous return to the heart. A major advance in food allergy was that humanized, monoclonal anti-IgE antibody showed protection against peanut-induced anaphylaxis. In addition to studies elucidating mechanisms of drug hypersensitivity, a clinical study showed patients with a history of prior penicillin allergy with negative penicillin allergy test results are unlikely to experience reactions or resensitization on subsequent oral courses of penicillin. Lastly, there are new recommendations for patients with convincing insect sting reaction histories but negative skin test responses to venom.

References

Feb 18, 2003·The Journal of Allergy and Clinical Immunology·Vibeke RosenfeldtAnders Paerregaard
Mar 15, 2003·The New England Journal of Medicine·Gideon LackUNKNOWN Avon Longitudinal Study of Parents and Children Study Team
Mar 15, 2003·The New England Journal of Medicine·Donald Y M LeungUNKNOWN Avon Longitudinal Study of Parents and Children Study Team
Sep 19, 2003·The Journal of Allergy and Clinical Immunology·Yuichi Teraki, Tetsuo Shiohara
Sep 19, 2003·The Journal of Allergy and Clinical Immunology·Raquel EmpedradRebecca S Gruchalla
Oct 18, 2003·The Journal of Allergy and Clinical Immunology·Songhui MaAnna Nowak-Wegrzyn
Oct 24, 2003·The New England Journal of Medicine·Brian L StromDan Pettitt
Nov 12, 2003·The Journal of Allergy and Clinical Immunology·Dhafer LaouiniRaif S Geha
Nov 12, 2003·The Journal of Allergy and Clinical Immunology·Araceli Díaz-PeralesGabriel Salcedo
Dec 6, 2003·The Journal of Allergy and Clinical Immunology·Jonathan M Spergel, Amy S Paller
Dec 6, 2003·The Journal of Allergy and Clinical Immunology·Natalija NovakDonald Y M Leung
Dec 6, 2003·The Journal of Allergy and Clinical Immunology·Mark BoguniewiczThomas Hultsch
Dec 6, 2003·The Journal of Allergy and Clinical Immunology·Kristian ReichAxel Schnuch
Dec 6, 2003·The Journal of Allergy and Clinical Immunology·Rhoda S KaganAnn E Clarke
Feb 6, 2004·The Journal of Allergy and Clinical Immunology·Sergio Romagnani

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Citations

Nov 19, 2004·Current Opinion in Pediatrics·Henry Milgrom
Oct 20, 2006·Pediatric Annals·Alessandro Fiocchi, Alberto Martelli
May 6, 2006·The Journal of Allergy and Clinical Immunology·Carina VenterTaraneh Dean
Jun 3, 2006·Pediatrics·Jill A PooleJill M Norris

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