Advances in aortic disease management: a year in review

Current Opinion in Cardiology
Vinay GargMark D Peterson

Abstract

The medical and surgical management of aortic disease is continually changing in search for improved outcomes. Our objective is to highlight recent advances in a few select areas pertaining to aortic disease and aortic surgery: the genetics of aortopathy, medical therapy of aortic aneurysms, advances in cardiac imaging, and operative strategies for the aortic arch. As our understanding of the genetic basis for aortopathy continues to improve, routine genetic testing may be of value in assessing patients with genetically triggered forms of aortic disease. With regard to medical advances, treating patients with Marfan syndrome with either losartan or atenolol at an earlier stage in their disease course improves outcomes. In addition, novel imaging indices such as wall shear stress and aortic stiffness assessed by MRI may become useful markers of aortopathy and warrant further study. With regard to the optimal technique for cerebral perfusion in aortic arch surgery, high-quality data are still lacking. Finally, in patients with complex, multilevel aortic disease, the frozen elephant trunk is a viable single-stage option compared with the conventional elephant trunk, although with an increased risk for spinal cord injury. Based on ...Continue Reading

References

May 16, 2014·The New England Journal of Medicine·Subodh Verma, Samuel C Siu
Jun 20, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Keijiro KatayamaTaijiro Sueda
Sep 1, 2014·The Journal of Thoracic and Cardiovascular Surgery·Leonard N GirardiSiyamek Neragi-Miandoab
Sep 18, 2014·The Journal of Thoracic and Cardiovascular Surgery·George MatalanisSean D Galvin
Oct 18, 2014·Journal of the American College of Cardiology·Judith Z GoldfingerValentin Fuster
Mar 5, 2015·The New England Journal of Medicine·Ronald V LacroLynn Mahony
Mar 5, 2015·The New England Journal of Medicine·Ziad Mallat, Alain Tedgui
Mar 15, 2015·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Malakh ShresthaMartin Czerny
Mar 31, 2015·The Journal of Thoracic and Cardiovascular Surgery·Malakh ShresthaAndreas Martens
Jul 21, 2015·The Annals of Thoracic Surgery·Bulat A ZiganshinJohn A Elefteriades
Aug 22, 2015·Journal of the American College of Cardiology·David G GuzzardiPaul W M Fedak

❮ Previous
Next ❯

Citations

Jun 14, 2017·Clinical Medicine Insights. Cardiology·Amit GoyalArya Mani
Apr 7, 2020·Interactive Cardiovascular and Thoracic Surgery·Shekhar SahaHeidi Niehaus
Aug 11, 2020·Journal of the Chinese Medical Association : JCMA·Hui-Hsuan KeChien-Kun Ting

❮ Previous
Next ❯

Methods Mentioned

BETA
dissections
prophylactic surgery
dissection

Related Concepts

Related Feeds

Aortic Coarctation

Aortic coarctation is a congenital condition characterized by narrowing of the aorta. Discover the latest research on this disease here.

Aortic Aneurysm

An aortic aneurysm is the weakening and bulging of the blood vessel wall in the aorta. This causes dilatation of the aorta, which is usually asymptomatic but carries the risk of rupture and hemorrhage. Find the latest research on aortic aneurysms here.

Cardiac Aneurysm

Aneurysm refers to a bulge of the wall or lining of a vessel commonly occurring in the blood vessels at the base of the septum or within the aorta. In the heart, it usually arises from a patch of weakened tissue in a ventricular wall, which swells into a bubble filled with blood. Discover the latest research on cardiac aneurysm here.

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.

© 2022 Meta ULC. All rights reserved