Advances in exercise, fitness, and performance genomics in 2011.

Medicine and Science in Sports and Exercise
Stephen M RothClaude Bouchard

Abstract

This review of the exercise genomics literature emphasizes the highest quality articles published in 2011. Given this emphasis on the best publications, only a small number of published articles are reviewed. One study found that physical activity levels were significantly lower in patients with mitochondrial DNA mutations compared with controls. A two-stage fine-mapping follow-up of a previous linkage peak found strong associations between sequence variation in the activin A receptor, type-1B (ACVRIB) gene and knee extensor strength, with rs2854464 emerging as the most promising candidate polymorphism. The association of higher muscular strength with the rs2854464 A allele was confirmed in two separate cohorts. A study using a combination of transcriptomic and genomic data identified a comprehensive map of the transcriptomic features important for aerobic exercise training-induced improvements in maximal oxygen consumption, but no genetic variants derived from candidate transcripts were associated with trainability. A large-scale de novo meta-analysis confirmed that the effect of sequence variation in the fat mass and obesity-associated (FTO) gene on the risk of obesity differs between sedentary and physically active adults. E...Continue Reading

References

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Sep 29, 2007·The Journal of Physiology·Alun G Williams, Jonathan P Folland
Nov 23, 2007·Journal of Applied Physiology·Helen D Kollias, John C McDermott
Apr 20, 2010·Medicine and Science in Sports and Exercise·Tuomo RankinenClaude Bouchard
Jun 17, 2010·British Journal of Sports Medicine·Eri MikamiMasashi Tanaka
Jul 14, 2010·Journal of Science and Medicine in Sport·Agnieszka MaciejewskaPaweł Cięszczyk
Aug 6, 2010·Nature·Tanya M TeslovichSekar Kathiresan
Aug 28, 2010·Medicine and Science in Sports and Exercise·Garrett I AshYannis P Pitsiladis
Oct 12, 2010·Journal of Applied Physiology·Pernille KellerJames A Timmons
Nov 13, 2010·International Journal of Sports Medicine·R M LimaR J Oliveira
Dec 25, 2010·Journal of Applied Physiology·Claude BouchardTuomo Rankinen
Jan 15, 2011·Medicine and Science in Sports and Exercise·Zi-Hong HeAlejandro Lucia
Jan 22, 2011·Journal of Applied Physiology·Richard L SeipPaul D Thompson
Jan 22, 2011·American Journal of Hypertension·Anders GrøntvedSøren Brage
Mar 11, 2011·Annals of the New York Academy of Sciences·Yi-Chun Loraine Tung, Giles S H Yeo
Apr 8, 2011·International Journal of Sports Medicine·L-L ChiuS S-Y Hsieh
Apr 19, 2011·Medicine and Science in Sports and Exercise·James M HagbergClaude Bouchard
Apr 29, 2011·The Journal of Clinical Endocrinology and Metabolism·Toni I PollinUNKNOWN Diabetes Prevention Program Research Group
Jun 24, 2011·Exercise and Sport Sciences Reviews·Claude Bouchard
Jun 28, 2011·Nature Genetics·Tuomas O KilpeläinenRuth J F Loos
Jul 30, 2011·PloS One·Shehnaz ApabhaiMichael I Trenell
Aug 27, 2011·Journal of Sports Sciences·David C HughesAlun G Williams
Nov 30, 2011·Journal of Sports Sciences·Agnieszka MaciejewskaIldus I Ahmetov

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Citations

Apr 20, 2014·Medicine and Science in Sports and Exercise·Bernd WolfarthClaude Bouchard
Mar 9, 2013·Medicine and Science in Sports and Exercise·Louis PérusseClaude Bouchard
Jan 19, 2013·Sports Medicine·Tobias EhlertDirk A Moser
May 18, 2013·Sports Medicine·Nir EynonDavid J Bishop
May 16, 2013·European Journal of Applied Physiology·Fatemeh KazeminasabJamal Moshtaghian
Jun 5, 2013·European Journal of Public Health·Heli ValkeinenRitva Prättälä
May 2, 2013·British Journal of Sports Medicine·Yannis PitsiladisAlejandro Lucia
Jan 29, 2013·Trends in Genetics : TIG·Scott A Kelly, Daniel Pomp
Nov 28, 2012·New Biotechnology·S GiampaoliV Romano Spica
Oct 15, 2013·Genes, Brain, and Behavior·E Kostrzewa, M J Kas
Aug 2, 2015·BMC Medical Genetics·Vincent P DiegoJosé A R Maia
Nov 13, 2014·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Melissa S Y ThongCornelis J F van Noorden
Sep 7, 2013·European Journal of Sport Science·André F SeabraJosé A Maia
Aug 29, 2013·International Journal of Sports Physiology and Performance·Myosotis MassiddaCarla M Calò
Feb 11, 2015·Journal of Applied Physiology·Anne HeckstedenTim Meyer
Feb 24, 2015·Medicine and Science in Sports and Exercise·Ruth J F LoosClaude Bouchard
Nov 25, 2016·Scandinavian Journal of Medicine & Science in Sports·H ZempoH Murakami
Sep 5, 2018·Behavioral Sciences·Nancy Vargas-MendozaJosé A Morales-González
Jan 16, 2014·Physiological Genomics·Thomas W BufordUNKNOWN LIFE Research Group

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