Advances in novel molecular targets for antidepressants.

Progress in Neuro-psychopharmacology & Biological Psychiatry
Qingzhong Wang, Yogesh Dwivedi

Abstract

Depression is the most common psychiatric illness affecting numerous people world-wide. The currently available antidepressant treatment presents low response and remission rates. Thus, new effective antidepressants need to be developed or discovered. Aiming to give an overview of novel possible antidepressant drug targets, we summarized the molecular targets of antidepressants and the underlying neurobiology of depression. We have also addressed the multidimensional perspectives on the progress in the psychopharmacological treatment of depression and on the new potential approaches with effective drug discovery.

References

Aug 21, 1990·European Journal of Pharmacology·R Trullas, P Skolnick
Jan 1, 1993·Psychopharmacology·W J McEntee, T H Crook
Nov 1, 1995·Pharmacology, Biochemistry, and Behavior·R T LayerP Skolnick
Dec 27, 1995·European Journal of Pharmacology·J L WileyR L Balster
Mar 26, 1997·European Journal of Pharmacology·R S MansbachY L Chen
Nov 5, 1997·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·L van LondenD De Wied
Mar 12, 1998·Biological Psychiatry·L van LondenD de Wied
Dec 9, 1998·Proceedings of the National Academy of Sciences of the United States of America·M BaradE Kandel
May 26, 1999·Pharmacology, Biochemistry, and Behavior·J M O'Donnell, S Frith
Nov 7, 1999·Progress in Brain Research·A Reid, D Willshaw
Feb 12, 2000·Trends in Pharmacological Sciences·N M Rupniak, M S Kramer
Feb 25, 2000·Biological Psychiatry·R M BermanJ H Krystal
May 30, 2001·The International Journal of Biochemistry & Cell Biology·S Harrison, P Geppetti
Jan 31, 2002·Annual Review of Medicine·Joel Berger, David E Moller
Jun 12, 2002·Canadian Journal of Physiology and Pharmacology·Nadia M J Rupniak
Jul 16, 2002·Pharmacology, Biochemistry, and Behavior·Paul M LeaAlan I Faden
Aug 13, 2002·Current Topics in Medicinal Chemistry·W Sieghart, G Sperk
Oct 4, 2002·Proceedings of the National Academy of Sciences of the United States of America·Benno RoozendaalTallie Z Baram
Oct 24, 2002·Trends in Neurosciences·Insuk Song, Richard L Huganir
Dec 7, 2002·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Ognen A C Petroff
Jun 6, 2003·Progress in Neuro-psychopharmacology & Biological Psychiatry·Cecile DucottetCatherine Belzung
Dec 11, 2003·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Mark S KramerYih Lee
Feb 6, 2004·European Journal of Pharmacology·Shigeyuki ChakiThomas Steckler
Mar 25, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Cedric MombereauJohn F Cryan
Aug 24, 2004·European Journal of Pharmacology·David H Overstreet, Guy Griebel
Aug 31, 2004·The Journal of Pharmacology and Experimental Therapeutics·David A SlatteryJohn F Cryan
Sep 15, 2004·European Journal of Pharmacology·Darci M NielsenLisa H Gold

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Current Pharmaceutical Design
Nikola KernJuliane Minkwitz
Expert Opinion on Drug Discovery
Christoph Anacker
The Mount Sinai Journal of Medicine, New York
Srijan Sen, Gerard Sanacora
© 2021 Meta ULC. All rights reserved