Advances in Omic Studies Drive Discoveries in the Biology of Anisakid Nematodes.

Genes
Stefano D'AmelioSerena Cavallero

Abstract

Advancements in technologies employed in high-throughput next-generation sequencing (NGS) methods are supporting the spread of studies that, combined with advances in computational biology and bioinformatics, have greatly accelerated discoveries within basic and biomedical research for many parasitic diseases. Here, we review the most updated "omic" studies performed on anisakid nematodes, a family of marine parasites that are causative agents of the fish-borne zoonosis known as anisakiasis or anisakidosis. Few deposited data on Anisakis genomes are so far available, and this still hinders the deep and highly accurate characterization of biological aspects of interest, even as several transcriptomic and proteomic studies are becoming available. These have been aimed at discovering and characterizing molecules specific to peculiar developmental parasitic stages or tissues, as well as transcripts with pathogenic potential as toxins and allergens, with a broad relevance for a better understanding of host-pathogen relationships and for the development of reliable diagnostic tools.

References

Jul 11, 2000·The Journal of Allergy and Clinical Immunology·I MoneoM J Alonso
Sep 26, 2000·Allergy·J A AsturiasA Martínez
Nov 4, 2000·International Archives of Allergy and Immunology·J Pérez-PérezC A Bedate
Feb 19, 2002·Trends in Parasitology·María Teresa AudicanaMalcolm W Kennedy
Aug 4, 2004·Molecular and Biochemical Parasitology·Kuniyoshi ShimakuraKazuo Shiomi
Apr 27, 2005·Nature Reviews. Molecular Cell Biology·V Narry Kim
May 17, 2005·Parasitology Research·Ignacio MoneoAugusto Silva
Dec 21, 2006·Parasitology Research·Yukihiro KobayashiKazuo Shiomi
Feb 3, 2007·International Journal of Dermatology·Fabrizio GuarneriSalvatore Benvenga
Feb 6, 2007·Trends in Parasitology·David P KnoxCollette Britton
Feb 28, 2007·International Journal for Parasitology·Ana I Rodriguez-MahilloIgnacio Moneo
Jun 15, 2007·Veterinary Parasitology·Makedonka MitrevaDouglas P Jasmer
Aug 11, 2007·Molecular and Biochemical Parasitology·Yukihiro KobayashiKazuo Shiomi
Sep 22, 2007·Science·Elodie GhedinAlan L Scott
Apr 2, 2008·Molecular and Biochemical Parasitology·Rosa Rodriguez-PerezMaria Luisa Caballero
May 15, 2009·Clinical and Experimental Immunology·A M AnadónF M Ubeira
Oct 27, 2009·PLoS Neglected Tropical Diseases·Paul J BrindleySara Lustigman
Feb 12, 2011·Parasitology International·Maria Luisa CaballeroRosa Rodriguez-Perez
May 10, 2011·International Journal for Parasitology·Benjamin ElsworthMark Blaxter
Sep 3, 2011·Trends in Parasitology·Aaron G MauleNikki J Marks
Oct 28, 2011·Nature·Aaron R JexRobin B Gasser
Jan 6, 2012·Parasitology·Johnathan J DalzellAaron G Maule
Aug 4, 2012·Veterinary Parasitology·Qusay Z M BahloolKurt Buchmann
Feb 9, 2013·RNA Biology·Yadong ZhengJanette E Bradley
Nov 12, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Namitha MohandasRobin B Gasser
Apr 1, 2014·Journal of Food Protection·Noelia Carballeda-SangiaoMiguel González-Muñoz
May 21, 2014·Allergy, Asthma & Immunology Research·Young-Bae Chung, Jaechun Lee
Jun 26, 2014·Parasitology·Mark Blaxter, Georgios Koutsovoulos
Aug 19, 2014·Surgery Today·Hideto SonodaYoshihiko Maehara
Sep 23, 2014·Parasitology Research·María Carmen RomeroJoaquina Martín-Sánchez
Dec 30, 2014·Journal of Extracellular Vesicles·Antonio MarcillaHernando A Del Portillo
Jan 28, 2015·Emerging Infectious Diseases·Hyemi LimJong-Yil Chai
Feb 17, 2015·International Journal for Parasitology·Juan González-FernándezCarmen Cuéllar
May 20, 2015·The Journal of Infectious Diseases·Sujittra ChaiyadetAlex Loukas
May 23, 2015·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Shan-Shan LiuYa-Biao Weng

❮ Previous
Next ❯

Citations

Dec 17, 2020·Animals : an Open Access Journal From MDPI·Juan C Ángeles-HernándezAndrea P Zepeda-Velázquez
Aug 23, 2020·Research in Veterinary Science·Francisco Javier Adroher-Auroux, Rocío Benítez-Rodríguez
Aug 28, 2021·Genes·Serena CavalleroStefano D'Amelio

❮ Previous
Next ❯

Datasets Mentioned

BETA
PRJEB496

Methods Mentioned

BETA
RNA-seq
one hybrid
environmental stress
electrophoresis
ELISA
proteomic profiling

Software Mentioned

Wormbase ParaSite

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.