Advances in radiation therapy of head and neck cancer

Expert Review of Anticancer Therapy
Aron Popovtzer, Avraham Eisbruch

Abstract

Head and neck cancer is the fifth most common cancer in the USA. Although there have been major improvements in surgical and radiation techniques, the overall survival has not changed significantly in the last decade. The major changes occurring in recent years have been in the ability to preserve organs and to improve quality of life. The advances in radiation therapy include 3D conformal radiotherapy, intensity-modulated radiotherapy and, more recently, imaging-guided radiotherapy. In advanced head and neck cancer the addition of chemotherapy to radiation has concomitantly improved survival and facilitated higher rates of organ preservation. Clinical trials are needed to develop better strategies customized to subgroups defined by individual biological risk and imaging findings.

References

Aug 1, 1991·Clinical Otolaryngology and Allied Sciences·H MaierG B Snow
Jun 13, 1991·The New England Journal of Medicine·UNKNOWN Department of Veterans Affairs Laryngeal Cancer Study GroupWilliam G Henderson
Mar 1, 1994·International Journal of Radiation Oncology, Biology, Physics·W H RoaA S Lichter
Apr 29, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M Al-SarrafJ F Ensley
Jul 7, 1999·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·W De NeveC De Waeter
Mar 4, 2000·International Journal of Radiation Oncology, Biology, Physics·R MohanR Schmidt-Ullrich
May 4, 2000·Journal of the National Cancer Institute·M L GillisonD Sidransky
Sep 7, 2000·International Journal of Radiation Oncology, Biology, Physics·P XiaL J Verhey
Apr 12, 2001·The New England Journal of Medicine·J MorkJ Dillner
Aug 23, 2001·International Journal of Radiation Oncology, Biology, Physics·N R SchechterK K Ang
Oct 13, 2001·International Journal of Radiation Oncology, Biology, Physics·E J AdamsS Webb
Jan 16, 2003·International Journal of Radiation Oncology, Biology, Physics·K S Clifford ChaoDaniel A Low
Feb 6, 2003·International Journal of Cancer. Journal International Du Cancer·Justine M RitchieThomas H Haugen
Feb 8, 2003·International Journal of Radiation Oncology, Biology, Physics·Christina TsienBenedick Fraass
May 14, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mirjam M J BraaksmaPeter C Levendag
Dec 3, 2003·The New England Journal of Medicine·Arlene A ForastiereJay Cooper
Feb 18, 2004·International Journal of Radiation Oncology, Biology, Physics·Tai-Xiang LuE Brian Butler
Mar 19, 2004·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Catharine H ClarkChristopher M Nutting
Apr 20, 2004·International Journal of Radiation Oncology, Biology, Physics·Avraham EisbruchGregory T Wolf
May 7, 2004·The New England Journal of Medicine·Jay S CooperUNKNOWN Radiation Therapy Oncology Group 9501/Intergroup
May 7, 2004·The New England Journal of Medicine·Jacques BernierUNKNOWN European Organization for Research and Treatment of Cancer Trial 22931
Sep 24, 2004·International Journal of Radiation Oncology, Biology, Physics·Jun-Etsu MizoeUNKNOWN Organizing Committee for the Working Group for Head-And-Neck Cancer
Nov 6, 2004·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·José A PeñagarícanoYulong Yan
Dec 14, 2004·International Journal of Radiation Oncology, Biology, Physics·Avraham EisbruchAlfons J M Balm
Jul 2, 2005·International Journal of Radiation Oncology, Biology, Physics·Angel I BlancoJoseph O Deasy
Sep 13, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mary FengAvraham Eisbruch
Nov 9, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ricardo HittHernán Cortés-Funes
Feb 10, 2006·The New England Journal of Medicine·James A BonnerK Kian Ang
Mar 1, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David G PfisterMichael J Zelefsky
Apr 4, 2006·Otolaryngologic Clinics of North America·Wounjhang Park, Jonathan M Owens
Jun 3, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Priscila M F Siesser, Steven K Hanks
Jun 3, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Marta CanelMaría-Dolores Chiara
Jan 24, 2007·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun
May 12, 2007·International Journal of Radiation Oncology, Biology, Physics·Nancy Y LeeDavid G Pfister
May 15, 2007·The New England Journal of Medicine·Gypsyamber D'SouzaMaura L Gillison
Jun 15, 2007·International Journal of Radiation Oncology, Biology, Physics·Felix Y FengAvraham Eisbruch
Oct 18, 2007·International Journal of Radiation Oncology, Biology, Physics·Jean-Pierre PignonUNKNOWN MACH-NC Collaborative Group
Oct 26, 2007·The New England Journal of Medicine·Jan B VermorkenUNKNOWN EORTC 24971/TAX 323 Study Group

❮ Previous
Next ❯

Citations

Oct 19, 2010·Radiation Oncology·Marta ScorsettiArmando Santoro
Feb 17, 2009·Current Oncology Reports·David N TeguhPaul I M Schmitz
Nov 17, 2015·Expert Review of Anticancer Therapy·Lucas Castro MendezGustavo Nader Marta
Jan 23, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Eugenio VanettiLuca Cozzi
Mar 17, 2009·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Arthur H FriedlanderEva E Chin
Jan 1, 2012·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·S A Syam KumarPadmanaban Sriram
Feb 24, 2011·Journal of Radiation Research·Koji ShinozakiEiji Nakayama

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Radiation Oncology, Biology, Physics
Niranjan BhandareWilliam M Mendenhall
© 2022 Meta ULC. All rights reserved