Advances in target therapy in lung cancer

European Respiratory Review : an Official Journal of the European Respiratory Society
Jean-Paul SculierAnne-Pascale Meert

Abstract

Herein, we have reviewed and analysed recent literature, published in 2013 and early 2014, in the context of pre-existing data. Considered target therapies were tyrosine kinase inhibitors of active epidermal growth factor receptor mutations (e.g. erlotinib, gefinitib and afatinib), anaplastic lymphoma kinase rearrangements (e.g. crizotinib) or angiogenesis (drugs under development), or monoclonal antibodies against vascular endothelial growth factor (e.g. bevacizumab) or epidermal growth factor receptors (e.g. cetuximab). The therapeutic project has to consider tyrosine kinase inhibitors in the case of nonsmall cell lung cancer with active epidermal growth factor receptor mutations or anaplastic lymphoma kinase rearrangement. However, these drugs should not be used in the absence of the targeted genetic abnormalities.

References

Jul 15, 2005·The New England Journal of Medicine·Frances A ShepherdUNKNOWN National Cancer Institute of Canada Clinical Trials Group
Jun 25, 2010·The New England Journal of Medicine·Makoto MaemondoUNKNOWN North-East Japan Study Group
Oct 29, 2010·The New England Journal of Medicine·Eunice L KwakA John Iafrate
Jan 22, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·William D TravisDavid Yankelewitz
Jul 23, 2011·The European Respiratory Journal·N GirardW Pao
Jan 31, 2012·The Lancet Oncology·Rafael RosellUNKNOWN Spanish Lung Cancer Group in collaboration with Groupe Français de Pneumo-Cancérologie and Associazione Italiana Oncologia T
Sep 13, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A InoueUNKNOWN North-East Japan Study Group
Nov 28, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J-C SoriaUNKNOWN meta-analysis of bevacizumab in advanced NSCLC collaborative group
Apr 19, 2013·Journal of the National Cancer Institute·Chee Khoon LeeJames Chih-Hsin Yang
Jun 4, 2013·The New England Journal of Medicine·Alice T ShawPasi A Jänne
Jul 3, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Lecia V SequistMartin Schuler
Jul 31, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Dae Ho LeeMauro Orlando
Aug 30, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J G AertsUNKNOWN NVALT Study Group
Nov 10, 2013·Nature Medicine·Curtis R Chong, Pasi A Jänne
Dec 18, 2013·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Jean-Louis PujolNick Thatcher
May 3, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Benjamin HaalandGilberto Lopes
May 21, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Tomoya KawaguchiAkihito Kubo
Aug 2, 2014·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Yi-Long WuMauro Orlando
Sep 30, 2014·The New England Journal of Medicine·Alice T ShawA John Iafrate
Dec 4, 2014·The New England Journal of Medicine·Benjamin J SolomonUNKNOWN PROFILE 1014 Investigators

❮ Previous
Next ❯

Citations

Feb 10, 2016·Diagnostic and Interventional Imaging·G R FerrettiA C Toffart
Jun 2, 2016·The European Respiratory Journal·Li Zhang, Joel Moss
Jan 7, 2017·BMC Complementary and Alternative Medicine·Yuan-Chiang ChungChih-Ping Hsu
Nov 25, 2016·Biomedical Reports·Tetsuya OguriAkio Niimi
Jan 5, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Weiwei KeZaiming Lu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arterial-Venous in Development & Disease

Arterial-venous development may play a crucial role in cardiovascular diseases. Here is the latest research.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Related Papers

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
Erin M Bertino, Gregory A Otterson
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
John D HainsworthAnthony Greco
© 2022 Meta ULC. All rights reserved