Advances in the enzymatic production of L-hexoses

Applied Microbiology and Biotechnology
Ziwei ChenWanmeng Mu

Abstract

Rare sugars have recently drawn attention because of their potential applications and huge market demands in the food and pharmaceutical industries. All L-hexoses are considered rare sugars, as they rarely occur in nature and are thus very expensive. L-Hexoses are important components of biologically relevant compounds as well as being used as precursors for certain pharmaceutical drugs and thus play an important role in the pharmaceutical industry. Many general strategies have been established for the synthesis of L-hexoses; however, the only one used in the biotechnology industry is the Izumoring strategy. In hexose Izumoring, four entrances link the D- to L-enantiomers, ketose 3-epimerases catalyze the C-3 epimerization of L-ketohexoses, and aldose isomerases catalyze the specific bioconversion of L-ketohexoses and the corresponding L-aldohexoses. In this article, recent studies on the enzymatic production of various L-hexoses are reviewed based on the Izumoring strategy.

References

Nov 1, 1995·The American Journal of Clinical Nutrition·G V LevinJ R Beadle
Dec 1, 1996·Glycobiology·S MuniruzzamanA D Elbein
Jun 6, 2002·Die Naturwissenschaften·Ken Izumori
Sep 21, 2004·Annual Review of Plant Biology·Malcolm A O'NeillAlan G Darvill
Oct 4, 2005·Journal of Bioscience and Bioengineering·Hiroyuki Sasahara, Ken Izumori
Oct 20, 2005·Journal of Bioscience and Bioengineering·Khim LeangKen Izumori
Oct 20, 2005·Journal of Bioscience and Bioengineering·Tom Birger GranströmKen Izumori
Oct 20, 2005·Journal of Bioscience and Bioengineering·Khim LeangKen Izumori
Feb 8, 2006·Applied and Environmental Microbiology·Hye-Jung KimDeok-Kun Oh
May 24, 2006·Journal of Biotechnology·Ken Izumori
Apr 27, 2007·Nature·Peter H Seeberger, Daniel B Werz
Jul 12, 2008·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Peter SaittaLance H Brown
Nov 6, 2008·Journal of Biotechnology·Ran-Young YoonDeok-Kun Oh
Jan 23, 2009·Applied Microbiology and Biotechnology·Ran-Young YoonDeok-Kun Oh
May 21, 2011·Bioscience, Biotechnology, and Biochemistry·Goro TakataKen Izumori
Jun 15, 2011·Journal of Agricultural and Food Chemistry·Wanmeng MuBo Jiang
Jul 19, 2011·Journal of Agricultural and Food Chemistry·Chia-Jui LinTsuei-Yun Fang
May 10, 2012·Applied Microbiology and Biotechnology·Wanmeng MuLeon Zhou
Dec 5, 2012·Journal of Bioscience and Bioengineering·Kenji MorimotoKen Izumori
Nov 10, 2013·Journal of Agricultural and Food Chemistry·Wenli ZhangWanmeng Mu
Dec 7, 2013·Acta Crystallographica. Section D, Biological Crystallography·Keiko UechiGoro Takata
Apr 22, 2015·Chemical Reviews·Tobias Gylling FrihedChristian Marcus Pedersen
May 29, 2015·Bioscience, Biotechnology, and Biochemistry·Yuji TeramiGoro Takata
Jul 8, 2015·Applied Microbiology and Biotechnology·Wanmeng MuBo Jiang

Citations

Jul 4, 2019·Applied Microbiology and Biotechnology·Fuzhi LuWanmeng Mu
May 7, 2020·Applied Microbiology and Biotechnology·Jiajun ChenWanmeng Mu
Jul 4, 2018·Applied Microbiology and Biotechnology·Zheng FangWanmeng Mu
Oct 23, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Zilei LiuGeorge W J Fleet

Related Concepts

Related Feeds

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.

Related Papers

Applied Microbiology and Biotechnology
Wanmeng MuBo Jiang
Chemical Reviews
Tobias Gylling FrihedChristian Marcus Pedersen
© 2021 Meta ULC. All rights reserved