Advances in time-of-flight PET

Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)
Suleman Surti, Joel S Karp

Abstract

This paper provides a review and an update on time-of-flight PET imaging with a focus on PET instrumentation, ranging from hardware design to software algorithms. We first present a short introduction to PET, followed by a description of TOF PET imaging and its history from the early days. Next, we introduce the current state-of-art in TOF PET technology and briefly summarize the benefits of TOF PET imaging. This is followed by a discussion of the various technological advancements in hardware (scintillators, photo-sensors, electronics) and software (image reconstruction) that have led to the current widespread use of TOF PET technology, and future developments that have the potential for further improvements in the TOF imaging performance. We conclude with a discussion of some new research areas that have opened up in PET imaging as a result of having good system timing resolution, ranging from new algorithms for attenuation correction, through efficient system calibration techniques, to potential for new PET system designs.

References

May 8, 1998·Physics in Medicine and Biology·A J ReaderR J Ott
Aug 4, 1998·IEEE Transactions on Medical Imaging·L Parra, H H Barrett
Sep 24, 2005·Physics in Medicine and Biology·Maurizio ContiVladimir Panin
Nov 22, 2007·Physics in Medicine and Biology·Paulo CrespoAndreas Wagner
Jan 1, 1994·IEEE Transactions on Medical Imaging·H M Hudson, R S Larkin
Jan 1, 1982·IEEE Transactions on Medical Imaging·L A Shepp, Y Vardi
Jan 1, 1982·IEEE Transactions on Medical Imaging·M M Ter-PogossianJ T Hood
Feb 22, 2008·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Joel S KarpGerd Muehllehner
May 8, 2008·Physics in Medicine and Biology·S Surti, J S Karp
Dec 23, 2008·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Maurizio Conti
Jul 21, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Dan J KadrmasDavid W Townsend
Jan 19, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Cristina LoisDavid W Townsend
Dec 2, 2010·Physics in Medicine and Biology·Maurizio Conti
Mar 24, 2011·Physics in Medicine and Biology·B W JakobyD W Townsend
Apr 6, 2011·Physics in Medicine and Biology·S SurtiJ S Karp
Oct 14, 2011·Medical Physics·V BettinardiM C Gilardi
Feb 1, 2012·Physics in Medicine and Biology·Michel DefriseJohan Nuyts
Aug 18, 2012·IEEE Transactions on Medical Imaging·Ahmadreza RezaeiJohan Nuyts
Sep 6, 2012·IEEE Transactions on Medical Imaging·Pieter MolletStefaan Vandenberghe
Jan 8, 2013·IEEE Transactions on Nuclear Science·Dan J KadrmasJames J Hamill
Apr 17, 2013·Physics in Medicine and Biology·Stefan SeifertDennis R Schaart
May 21, 2013·Physics in Medicine and Biology·M E Werner, J S Karp
Oct 1, 2013·IEEE Transactions on Nuclear Science·Eunsin LeeSuleman Surti
Feb 28, 2014·Journal of Instrumentation : an IOP and SISSA Journal·W-S ChoongW W Moses
Mar 8, 2014·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Margaret E Daube-WitherspoonJoel S Karp
Jun 24, 2014·Physics in Medicine and Biology·Jeffrey A KolthammerRaymond F Muzic
Aug 29, 2014·Physics in Medicine and Biology·Harold RothfussMichael Casey
Dec 9, 2014·IEEE Transactions on Nuclear Science·W J AshmanskasJ S Karp Fellow
Dec 20, 2014·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Suleman Surti
Jan 31, 2015·Physics in Medicine and Biology·Florian R SchneiderSibylle I Ziegler

❮ Previous
Next ❯

Citations

Oct 13, 2016·The British Journal of Radiology·Stephan WalrandFrançois Jamar
Jan 27, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Edwin E G W Ter VoertGaspar Delso
Apr 10, 2017·Magnetic Resonance Imaging Clinics of North America·Ciprian Catana
Apr 4, 2017·Physics in Medicine and Biology·Haewook ParkJae Sung Lee
Jul 19, 2017·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Jae Sung LeeDong Soo Lee
Jul 28, 2017·Physics in Medicine and Biology·Hamidreza HemmatiPardis Ghafarian
Jun 22, 2019·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Masao WatanabeKaori Togashi
Mar 4, 2020·Sensors·Sandra OliverM J Rodríguez-Álvarez
Mar 28, 2019·Frontiers in Medicine·Eric J MeesterMarion de Jong
Jun 25, 2019·Nuclear Medicine and Molecular Imaging·Antonella MattiStefano Fanti
May 27, 2020·EJNMMI Physics·Stefaan VandenbergheJoel S Karp
Nov 29, 2017·Physics in Medicine and Biology·Eric Berg, Simon R Cherry
Nov 4, 2017·Contrast Media & Molecular Imaging·Chadwick L WrightMichael V Knopp
Jun 3, 2016·The Review of Scientific Instruments·E E ErmisE Pilicer
Aug 5, 2017·Frontiers in Neuroscience·Martin L LassenMartin Bauer
Oct 3, 2018·Contrast Media & Molecular Imaging·Francesca GallivanoneIsabella Castiglioni
Feb 29, 2020·Physics in Medicine and Biology·Stefan Gundacker, Arjan Heering
Nov 26, 2020·AJR. American Journal of Roentgenology·Masao WatanabeKaori Togashi
Dec 22, 2020·Physics in Medicine and Biology·Lisa BlackbergHamid Sabet
May 21, 2020·Physics in Medicine and Biology·Paul LecoqMathieu Benoit
Jun 2, 2018·Seminars in Nuclear Medicine·Eric Berg, Simon R Cherry
Feb 12, 2021·Physics in Medicine and Biology·Lisa BläckbergHamid Sabet
Mar 12, 2021·Frontiers in Medicine·Olivier DelcroixSolène Querellou
Aug 10, 2020·PET Clinics·Mahsa AmirrashediMohammad Reza Ay
Mar 13, 2021·Physics in Medicine and Biology·Chunhui ZhangZheng Liu
Dec 19, 2020·Physics in Medicine and Biology·Steven R MeikleJoyita Dutta
Jun 13, 2018·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Amir GhabrialHabib Zaidi
Jun 20, 2020·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Stephane ChauvieRoberta Matheoud
Mar 25, 2021·EJNMMI Physics·Vanessa NadigVolkmar Schulz
Mar 25, 2021·Physics in Medicine and Biology·Shirin PourashrafCraig S Levin
Apr 14, 2021·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Hunor KertészPeter L Kench
Mar 13, 2021·Physics in Medicine and Biology·Dennis R Schaart
Jun 23, 2019·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Joel S KarpMargaret E Daube-Witherspoon
Jan 8, 2017·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Hanna SvirydenkaEdwin E G W Ter Voert
Jun 23, 2021·Optics Express·Cesar Bartolo-PerezGerard Ariño-Estrada
Feb 6, 2021·Physics in Medicine and Biology·Andy LaBellaAmir H Goldan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Seminars in Nuclear Medicine
Piotr J SlomkaGuido Germano
Radiologic Clinics of North America
Adam M AlessioJoel S Karp
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Bernd J PichlerMartin S Judenhofer
Current Opinion in Obstetrics & Gynecology
Paul D Blumenthal
Nuclear Instruments & Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment
William W Moses
© 2022 Meta ULC. All rights reserved