Advances on graphene-based nanomaterials for biomedical applications

Materials Science & Engineering. C, Materials for Biological Applications
Ying QuJingde Wu

Abstract

Graphene-based nanomaterials, such as graphene oxide and reduced graphene oxide, have been attracting increasing attention in the field of biology and biomedicine over the past few years. Incorporation of these novel materials with drug, gene, photosensitizer and other cargos to construct novel delivery systems has witnessed rapid advance on the basis of their large surface area, distinct surface properties, excellent biocompatibility and pH sensitivity. Moreover, the inherent photothermal effect of these appealing materials enables them with the ability of killing targeting cells via a physical mechanism. Recently, more attentions have been attached to tissue engineering, including bone, neural, cardiac, cartilage, musculoskeletal, and skin/adipose tissue engineering, due to the outstanding mechanical strength, stiffness, electrical conductivity, various two-dimensional (2D) and three-dimensional (3D) morphologies of graphene-based nanomaterials. Herein, emerging applications of these nanomaterials in bio-imaging, drug/gene delivery, phototherapy, multimodality therapy and tissue engineering were comprehensively reviewed. Inevitably, the burgeon of this kind of novel materials leads to the endeavor to consider their safety so ...Continue Reading

Citations

Jan 8, 2020·Drug and Chemical Toxicology·Shiv Kumar PrajapatiAakanchha Jain
Dec 15, 2019·Nanomaterials·Daniela Plachá, Josef Jampilek
Sep 27, 2020·Materials·Karolina MatulewiczAnna Bajek
Apr 24, 2020·Journal of Biomedical Materials Research. Part a·Milena StevanovićVesna Mišković-Stanković
Sep 5, 2019·Nanomaterials·Giulia NeriAnna Piperno
Feb 11, 2021·Nanomaterials·Pietro BelletFrancesco Filippini
Feb 9, 2021·Bioactive Materials·Keshav Narayan AlagarsamySanjiv Dhingra
Feb 19, 2021·Nanoscale·Roberta FabbriValentina Benfenati
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Nicolò MauroGennara Cavallaro
Sep 9, 2019·ACS Biomaterials Science & Engineering·Elizabeth CampbellAnton V Naumov

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