Advancing Methods of Assessing Bone Quality to Expand Screening for Osteoporosis

The Journal of the American Osteopathic Association
Carolyn KomarLaurie Bauer

Abstract

Dual-energy x-ray absorptiometry (DXA) limits osteoporosis screening because of machine size, technical requirements for operation, and exposure to ionizing radiation. To establish data ranges from calcaneus ultrasonography (US) that correspond to bone mineral density (BMD) stratification identified by DXA and to determine whether vitamin D concentration adds to US bone health assessment. Patients scheduled for DXA at the Robert C. Byrd Clinic, a rural primary care facility in Lewisburg, West Virginia, were recruited from June 2015 to June 2016. Ultrasonography was used to scan the left and right calcaneus of the patients, and blood was collected from a finger prick for vitamin D analysis. Information was collected regarding Fracture Risk Assessment tool parameters, menstrual history, and drug and supplement use. The correlations within and between DXA and US measurements were calculated, as well as the correlations between DXA and US measurements and vitamin D levels. Predictive performance of US readings on bone health determined by DXA scan was assessed with area under the curve analysis using receiver operator characteristic curves. Ninety-nine participants were included. Ultrasonography readings of either the left or right...Continue Reading

References

Mar 21, 2001·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C F NjehH K Genant
Mar 21, 2001·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R P HeaneyC Weaver
Apr 8, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Claus C GlüerSami Kolta
Aug 5, 2009·European Journal of Radiology·Giuseppe Guglielmi, Francesca de Terlizzi
Jun 8, 2011·The Journal of Clinical Endocrinology and Metabolism·Michael F HolickUNKNOWN Endocrine Society
Nov 5, 2013·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·John T SchousboeSanford Baim
Nov 26, 2013·International Journal of Medical Sciences·Kok-Yong Chin, Soelaiman Ima-Nirwana
May 21, 2016·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M D WalkerS J Silverberg

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Citations

Feb 26, 2019·The Journal of the American Osteopathic Association·Jandy B Hanna, Craig S Boisvert
Oct 31, 2019·American Journal of Physical Anthropology·Felicia C MadimenosJonathan Stieglitz
Oct 3, 2020·JBJS Reviews·Bassel G DieboCarl B Paulino

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