Advantages of using estimated depression-free days for evaluating treatment efficacy.

Psychiatric Services : a Journal of the American Psychiatric Association
Steven D VannoyJürgen Unützer

Abstract

Several common methods for measuring treatment response present a snapshot of depression symptoms. The construct of estimated depression-free days (DFDs) simultaneously captures treatment outcome and estimates the patient's experience of depression over time. The study compared this measure with traditional measures used in depression treatment research. This secondary data analysis was based on data from the Improving Mood-Promoting Access to Collaborative Treatment trial, a multisite depression treatment study conducted in 18 primary care clinics in five states and representing eight health care systems. The sample of older adults (N=906) had been randomly assigned to receive collaborative care for depression. Participants were aged 60 or older and met criteria for major depressive disorder, dysthymia, or both. Exclusion criteria included severe cognitive impairment, active substance abuse, active suicidal behavior, severe mental illness, and active treatment from a psychiatrist. The Patient Health Questionnaire (PHQ-9) and the Hopkins Symptom Checklist (HSCL-20) were used as outcome measures at four assessment points (baseline, three months, six months, and 12 months). Outcomes were computed for relative change, standardized...Continue Reading

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Citations

Apr 1, 2014·Journal of Affective Disorders·Enric AragonèsJuan Cabasés
Feb 5, 2013·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Klemen Naveršnik, Aleš Mrhar
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Jul 30, 2021·Psychiatric Services : a Journal of the American Psychiatric Association·Jennifer M BoggsZindel V Segal
Oct 12, 2021·Journal of the American Geriatrics Society·Kai YeungMichael V Vitiello

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