PMID: 3751750Jul 1, 1986Paper

Adverse drug reactions: an investigation on an acute geriatric ward

Age and Ageing
S Leach, S S Roy

Abstract

A total of 521 patients consecutively admitted to an acute geriatric unit were kept under surveillance by one observer during their stay. All drugs given to them and the occurrence of adverse events were recorded. One hundred and seventeen adverse drug reactions occurred in 94 patients representing 18.8% of the 500 patients receiving drugs. Thirteen of these reactions were considered severe. Each patient received an average of 6.1 drugs, not necessarily simultaneously. Altogether 212 different drug preparations were used. Diamorphine and insulin had the highest adverse reaction rates, diamorphine having the highest risk of a severe adverse reaction. Antibiotics and diuretics caused the most adverse reactions, and were by far the most commonly prescribed drugs (26.5% of the sample). Of the patients receiving eight or more drugs, 41% suffered an adverse drug reaction.

Citations

Sep 15, 2001·European Journal of Internal Medicine·J -B. WasserfallenJ Biollaz
Jan 10, 2001·Alimentary Pharmacology & Therapeutics·H DormannH T Schneider
Jul 3, 2004·BMJ : British Medical Journal·Munir PirmohamedAlasdair M Breckenridge
Aug 14, 2012·Drug, Healthcare and Patient Safety·Anita ConfortiRoberto Leone
Mar 25, 2008·Therapeutics and Clinical Risk Management·Sarah N HilmerDavid G Le Couteur
Jul 11, 2012·Drugs & Aging·Balamurugan TangiisuranChakravarthi Rajkumar
Nov 3, 2010·British Journal of Clinical Pharmacology·Emma C DaviesMunir Pirmohamed
Jan 27, 2007·The Cochrane Database of Systematic Reviews·N A de MortonK Jeffs
May 1, 1994·Journal of the American Geriatrics Society·R M PalmerJ Kowal
Dec 4, 1998·Scottish Medical Journal·G Cunningham
Feb 1, 1990·DICP : the Annals of Pharmacotherapy·S D KarkiE Mariano

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