PMID: 11903512Mar 21, 2002Paper

Adverse drug reactions: keeping up to date

Fundamental & Clinical Pharmacology
J K AronsonYoon K Loke

Abstract

The amount of published literature on adverse drug reactions is overwhelming; for example, the serial publication Side Effects of Drugs Annual lists and critically discusses over 3000 references each year. As a group, pharmacotherapeutics journals publish more papers on adverse drug reactions than journals that cover other fields, but even so they publish a minority of the total number of papers, and no single journal or group of journals can be highlighted as being a frequent source of primary information. Non-specialists must therefore rely on secondary literature (reviews) and tertiary literature (critical summaries) for information. Most of the primary published literature is in the form of anecdotal reports (30%) and formal studies or randomized controlled trials (35%). The anecdotal reports vary in quality; a new serial publication devoted to this type of article would bring some of the literature together and would improve the quality of reporting. Although many of the randomized controlled trials are of good quality and large enough to reveal benefit, most are too small to provide robust information about adverse drug reactions. Systematic reviews are too few in number (only 1.25% of publications on adverse drug reactio...Continue Reading

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Citations

Feb 10, 2006·Health Information and Libraries Journal·Su GolderUNKNOWN Centre for Reviews and Dissemination and UK Cochrane Centre Search Filters Design Group
Aug 18, 2010·Health Information and Libraries Journal·Su Golder, Yoon K Loke
Jun 21, 2003·BMJ : British Medical Journal·Jeffrey K Aronson
Jul 12, 2003·BMJ : British Medical Journal·Luis Gabriel Cuervo, Mike Clarke
Jul 15, 2006·BMJ : British Medical Journal·R E Ferner, J K Aronson
Jan 20, 2006·BMJ : British Medical Journal·Yoon Kong LokeJeffrey K Aronson
Jan 10, 2014·BMJ : British Medical Journal·Liliane ZorzelaSunita Vohra
Jul 21, 2004·BMC Medical Research Methodology·Heather M McIntoshAnne-Marie Bagnall
Nov 15, 2003·BMC Clinical Pharmacology·Edward MillsDavid Juurlink
Apr 9, 2005·Journal of Evaluation in Clinical Practice·Jeffrey K Aronson
Jan 30, 2004·Fundamental & Clinical Pharmacology·Maryse Lapeyre-MestreJean-Louis Montastruc
Apr 20, 2004·British Journal of Clinical Pharmacology·Yoon K LokeJeffrey K Aronson
Mar 29, 2011·Pharmacoepidemiology and Drug Safety·Winfried RiefElmar Braehler
Dec 19, 2014·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Barbara Osimani, Fiorenzo Mignini
Apr 1, 2011·Therapeutic Advances in Drug Safety·Yoon K LokeJan P Vandenbroucke
Dec 5, 2002·Pharmacoepidemiology and Drug Safety
Mar 28, 2008·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Jeffrey K Aronson
Aug 13, 2010·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Piero Impicciatore, Massimiliano Mucci
Feb 25, 2009·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Manfred Hauben, Jeffrey K Aronson
May 29, 2015·Expert Review of Clinical Pharmacology·Jeffrey K Aronson

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