Adverse effects in workers exposed to inorganic lead

Arhiv za higijenu rada i toksikologiju
Saso StoleskiJordan Minov

Abstract

This paper describes a retrospective cohort study comparing 60 workers occupationally exposed to inorganic lead and 60 matched controls. All subjects were assessed using data obtained from a specially designed Questionnaire for lead exposure and toxic effects assessment, physical examination, spirometry, ECG, and laboratory tests including blood lead level (BLL) and biomarkers of lead toxic effects. Muscle pain, droopiness, and work-related nasal symptoms were significantly more frequent in lead workers. The prevalence of lung symptoms was higher in lead workers than in controls, but not significantly (20 % vs. 6.6 %, respectively). Mean values of BLL and delta-aminolevulinic acid (ALA) were significantly higher in lead workers. The activity of delta-aminolevulinic acid dehydratase (ALAD) in lead workers was significantly lower than in controls. Abnormal of BLL, ALAD, and ALA were more frequent in lead workers, with statistical difference for BLL and ALAD. Inverse correlation was found between BLL and ALAD, and positive correlation between BLL and age, years of employment, and years of exposure. Inverse correlation was found between ALAD and age, years of employment, years of exposure, blood pressure, alcohol consumption, and y...Continue Reading

References

Jan 1, 1992·Human & Experimental Toxicology·D NewtonJ S Hislop
Oct 1, 1991·Environmental Research·S K RastogiS Srivastava
Oct 1, 1991·The Journal of Pediatrics·M D McElvaineR M Krieg
Jun 1, 1990·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·C MorrisW M Bennett
Jan 1, 1986·International Archives of Occupational and Environmental Health·B ZiemsenH W Goedde
Jan 1, 1984·International Archives of Occupational and Environmental Health·M DossM Stoeppler
Oct 6, 1984·British Medical Journal·S J PocockT P Whitehead
Aug 1, 1984·Scandinavian Journal of Work, Environment & Health·S TelismanS Kezić
Jan 1, 1982·International Archives of Occupational and Environmental Health·S TelismanD Prpić-Majić
Jul 1, 1981·Annals of Human Genetics·G BattistuzziS Caiola
Jan 1, 1997·Environmental Research·H L Needleman
May 17, 2000·Industrial Health·T Sakai
Jun 28, 2001·American Journal of Epidemiology·S N KeladaM J Khoury
Jan 26, 2002·Archives of Toxicology·H W KuoJ S Lai
Mar 9, 2002·The Science of the Total Environment·P ApostoliC Minoia
Jun 19, 2002·International Journal of Hygiene and Environmental Health·Kerstin BeckerBernd Seifert

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Citations

Dec 14, 2011·International Archives of Occupational and Environmental Health·V KašubaA Jazbec
Nov 4, 2008·Biological Trace Element Research·A Ustundag, Y Duydu
Jan 8, 2013·Biological Trace Element Research·Gagan FloraArchana Tiwari
Dec 3, 2014·Toxicology and Applied Pharmacology·Itzel-Citlalli Aguilar-DoradoJosé-Víctor Calderón-Salinas
Jan 19, 2011·Mutation Research·Julia García-LestónBlanca Laffon
Dec 23, 2014·Women & Health·Osmel La-Llave-LeónGonzalo García-Vargas
Nov 25, 2018·Basic & Clinical Pharmacology & Toxicology·Samaneh NakhaeeOmid Mehrpour
Jan 18, 2018·Archives of Environmental & Occupational Health·Zertashia AkramIshrat Mahjabeen
Oct 31, 2017·Annals of Human Biology·Bert B LittleDavid L Wiegman

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