Adverse effects of admission blood alcohol on long-term cognitive function in patients with traumatic brain injury

The Journal of Trauma and Acute Care Surgery
Bellal JosephPeter Rhee

Abstract

Alcohol is known to be protective in patients with traumatic brain injury (TBI); however, its impact on the long-term cognitive function is unknown. We hypothesize that intoxication at the time of injury is associated with adverse long-term cognitive function in patients sustaining TBI. We performed a 2-year retrospective study of all trauma patients with isolated TBI presenting to our Level I trauma center and discharged to a single rehabilitation facility. Patients with moderate-to-severe TBI (head Abbreviated Injury Scale [AIS] score ≥ 3), measured admission blood alcohol concentration, and measured cognitive function on hospital discharge and rehabilitation center discharge were included. Cognitive function was assessed using Functional Independence Measure (FIM) scores. Delta cognitive FIM was defined as the difference between rehabilitation center discharge and hospital discharge cognitive FIM scores. Multivariate linear regression was performed. A total of 64 patients were included. Mean (SD) age was 51.8 (23) years, median head AIS score was 3 (IQR, 3-5), and median Glasgow Coma Scale (GCS) score was 11 (IQR, 3-15). Mean (SD) cognitive FIM score on hospital discharge was 17 (6), and mean (SD) cognitive improvement was 8...Continue Reading

References

Dec 11, 2002·Archives of Physical Medicine and Rehabilitation·Charles H BombardierHeather Zintel
Sep 6, 2006·Neuropsychological Rehabilitation·Beth L Parry-JonesW Miles Cox

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Citations

Feb 2, 2016·American Journal of Physical Medicine & Rehabilitation·Farid F MuakkassaAnthony Hayek
Sep 3, 2016·Neuropsychological Rehabilitation·J L Mathias, A J Osborn
Oct 27, 2016·Plastic and Reconstructive Surgery·Jonas KolbenschlagOle Goertz
Jun 28, 2017·Alcoholism, Clinical and Experimental Research·Qiuping DingLiang Shen
Jan 8, 2019·Journal of Neuroscience Research·Son T TonGwendolyn L Kartje
Aug 19, 2016·Journal of the International Neuropsychological Society : JINS·Noah D SilverbergRael T Lange
Jun 30, 2019·World Neurosurgery·Calvin C WhaleyBrandon G Gaynor

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