Adverse effects of coexistence of sarcopenia and metabolic syndrome in Japanese women

European Journal of Clinical Nutrition
Kiyoshi SanadaMotohiko Miyachi

Abstract

Little information is available regarding the interactions of sarcopenia and metabolic syndrome (MetS) in the risks of these age-associated diseases in women. The present cross-sectional study was performed to investigate whether the coexistence of sarcopenia and MetS further increases the risks of lifestyle-related diseases in Japanese women. Healthy Japanese women (n=533) aged 30-84 participated in this study. MetS was defined as higher body mass index, fasting plasma glucose, systolic or diastolic blood pressure and blood lipid abnormalities. Appendicular muscle mass and bone mineral density (BMD) were measured using dual-energy X-ray absorptiometry. The criterion of low muscle mass and strength defined median skeletal muscle index (appendicular muscle mass/height², kg/m²) and handgrip strength. Two-way ANCOVA with adjustment for age, body fat percentage and whole-body lean tissue mass indicated that sarcopenia and MetS interacted to produce a significant effect on HbA1c, systolic blood pressure, triglycerides and brachial-ankle pulse wave velocity in Japanese women. The systolic blood pressure, triglycerides and brachial-ankle pulse wave velocity were significantly higher in women with coexisting sarcopenia and MetS than in...Continue Reading

References

May 1, 1991·Journal of Gerontology·N B AlexanderD N Warwick
Apr 1, 1991·Medicine and Science in Sports and Exercise·S E PetersonE L Smith
Jul 1, 1990·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·J P DesprésC Bouchard
Feb 1, 1990·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P B GleesonH J Evans
Feb 1, 1993·The Journal of Nutrition·W J Evans, W W Campbell
Aug 31, 1999·Journal of Hypertension·J N Cohn
Apr 6, 2000·Journal of Applied Physiology·W R FronteraR Roubenoff
Dec 29, 2000·Medicine and Science in Sports and Exercise·S CarrollR J Butterly
Dec 29, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·R Roubenoff, V A Hughes
Nov 8, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S M PluijmP Lips
Aug 6, 2003·Medicine and Science in Sports and Exercise·Timo A LakkaJukka T Salonen
Oct 14, 2003·Journal of Applied Physiology·Fulvio LauretaniLuigi Ferrucci
Feb 10, 2004·Arteriosclerosis, Thrombosis, and Vascular Biology·Scott M GrundyUNKNOWN American Heart Association
Oct 27, 2004·Diabetes Care·James B Meigs
Dec 23, 2004·Journal of Hypertension·Marieke B SnijderCoen D A Stehouwer
Feb 25, 2005·Journal of Human Hypertension·J SugawaraH Tanaka
Apr 13, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Pawel SzulcPierre D Delmas
Jul 5, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Marianne C WalshMargaret Barbara Livingstone
May 2, 2006·Journal of the American Dietetic Association·Carrie E FinleyMilton Z Nichaman
Nov 11, 2006·Journal of Applied Physiology·Matthew A SchragerLuigi Ferrucci
Dec 26, 2006·Obesity·Mylène Aubertin-LeheudreIsabelle J Dionne
May 12, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D von MuhlenE Barrett-Connor
May 29, 2007·Internal Medicine·Kazuo TakahashiShuhei Yamaguchi
Sep 6, 2007·The Journal of Clinical Endocrinology and Metabolism·Mitsuyo KinjoDaniel H Solomon
Sep 13, 2007·Journal of Endocrinological Investigation·G CrepaldiG Paolisso
Apr 25, 2009·The Journal of Nutrition, Health & Aging·W C Stephen, I Janssen
May 14, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D L WatersA Goulding
Jul 1, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D-K Hwang, H-J Choi
Apr 16, 2010·Age and Ageing·Alfonso J Cruz-JentoftUNKNOWN European Working Group on Sarcopenia in Older People
Jul 9, 2010·Menopause : the Journal of the North American Menopause Society·José L HernándezJesús González-Macías

❮ Previous
Next ❯

Citations

Oct 5, 2013·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·David L KendlerJohn Shepherd
Sep 3, 2013·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Ho Cheol HongKyung Mook Choi
Mar 16, 2017·World Journal of Hepatology·Cristiane V TovoAngelo A de Mattos
Jul 15, 2017·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Andrea ArmaniMassimiliano Caprio
Mar 7, 2020·International Journal of Environmental Research and Public Health·Kanako HamaguchiKiyoshi Sanada
Oct 24, 2014·World Journal of Gastroenterology : WJG·Marco BertolottiPaola Loria
Apr 11, 2018·Diabetology & Metabolic Syndrome·Heloísa TrierweilerVictória Zeghbi Cochenski Borba
Mar 7, 2017·Geriatrics & Gerontology International·Atsumu YukiHiroshi Shimokata
Jun 29, 2017·Clinical and Experimental Pharmacology & Physiology·Alexander J RodríguezDavid Scott
May 1, 2021·Metabolites·Gregory HabigDina Halegoua-DeMarzio
Jul 22, 2021·Arquivos brasileiros de cardiologia·Flávia Veríssimo Melo E SilvaRoberto Dischinger Miranda

❮ Previous
Next ❯

Related Concepts

Related Feeds

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Biomarkers for Type 2 Diabetes

Biomarkers can help understand chronic diseases and assist in risk prediction for prevention and early detection of diseases. Here is the latest research on biomarkers in type 2 diabetes, a disease in which the body is unable to produce or properly use insulin.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.