Adverse effects of interrupting precordial compression during cardiopulmonary resuscitation

Critical Care Medicine
Y SatoJ Bisera

Abstract

In the current operation of automated external defibrillators, substantial time may be consumed for a "hands off" interval during which precordial compression is discontinued to allow for automated rhythm analyses before delivery of the electric countershock. The effects of such a pause on the outcomes of cardiopulmonary resuscitation were investigated. Prospective, randomized, controlled animal study. Research laboratory. Male Sprague-Dawley rats. Ventricular fibrillation was electrically induced in 25 Sprague-Dawley rats. After 4 mins of untreated ventricular fibrillation, precordial compression was begun and continued for 6 mins. Animals were then randomized to receive an immediate defibrillation shock or the defibrillation attempt was delayed for intervals of 10, 20, 30, or 40 secs. Immediate defibrillation restored spontaneous circulation in each instance. When defibrillation was delayed for 10 or 20 secs, spontaneous circulation was restored in three of five animals in each group. After a 30-sec delay, spontaneous circulation was restored in only one of five animals (p < .05). No animal was successfully resuscitated after a 40-sec delay (p < .01). With increasing delays, 24- and 48-hr survival rates were correspondingly r...Continue Reading

References

Oct 8, 1992·The New England Journal of Medicine·J T Niemann
Apr 1, 1990·Journal of Applied Physiology·C V GudipatiE C Rackow
Feb 1, 1990·Annals of Emergency Medicine·K M HargartenJ C Darin
Feb 23, 1990·JAMA : the Journal of the American Medical Association·N A ParadisR M Nowak
Jul 17, 1986·The New England Journal of Medicine·M H WeilM I Griffel
Nov 1, 1986·Circulation·W GrundlerE C Rackow
Dec 1, 1988·Journal of Applied Physiology·I von PlantaE C Rackow
Sep 15, 1988·The New England Journal of Medicine·W D WeaverA P Hallstrom
May 1, 1987·The American Journal of Emergency Medicine·R O Cummins
Jun 19, 1980·The New England Journal of Medicine·M S EisenbergL A Cobb
Jul 1, 1995·Critical Care Medicine·C DuggalS Sun
Apr 1, 1995·Journal of Applied Physiology·B A JohnsonD McCandless
Jan 1, 1993·Journal of Applied Physiology·C DuggalM Ali
Jun 1, 1996·Critical Care Medicine·R J GazmuriD McKee
Sep 1, 1958·Circulation Research·W P McKEEVERP C CANNEY

❮ Previous
Next ❯

Citations

Jul 1, 1997·Disease-a-month : DM·M H Weil, W Tang
Mar 30, 2001·Resuscitation·A LanghelleP A Steen
Apr 2, 2003·Resuscitation·Matthew J ReedColin E Robertson
Sep 13, 2003·Resuscitation·Douglas ChamberlainMichael Colquhoun
Mar 9, 2004·Resuscitation·Douglas ChamberlainUNKNOWN Excecutive Committee European Resuscitation Council
May 13, 1999·Critical Care Medicine·M NocJ Bisera
Jan 22, 2002·Critical Care Medicine·A Marn-PernatJ Bisera
Oct 29, 2004·Critical Care Medicine·Carlos CastilloMax Harry Weil
May 14, 2005·Critical Care Medicine·Stephan C U MarschPatrick R Hunziker
Feb 22, 2008·Journal of Veterinary Internal Medicine·S J Plunkett, M McMichael
Jan 8, 2010·Biomedical Engineering Online·Anton AmannWerner Lingnau
Jul 6, 2014·Resuscitation·Daniel L LemkinMark A Lemkin
Feb 3, 2016·Australasian Physical & Engineering Sciences in Medicine·Ming YuFeng Chen
Oct 11, 2015·The Journal of Emergency Medicine·Allison C KollerJames J Menegazzi
Nov 20, 2012·The American Journal of Emergency Medicine·Lars Koch HansenMikkel Brabrand
May 29, 2012·The American Journal of Emergency Medicine·Lee M CunninghamWilliam J Brady
May 3, 2011·The American Journal of Emergency Medicine·Amal MattuWilliam J Brady
Feb 13, 2009·Resuscitation·Robert Sebastian HokeKarl Werdan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.