Adverse histopathological findings in glottic cancer with anterior commissure involvement

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Małgorzata LeszczyńskaMałgorzata Wierzbicka

Abstract

Open partial horizontal laryngectomy (OPHL) specimens include cartilage and lymph nodes. Pathological adverse findings (PAF): perichondrium, cartilage, perineural invasion, microvessel spread and prelaryngeal metastases can be detected histologically. We aimed at examining PAF in OPHL specimens and examining the interdependence with oncological outcomes. Prospective analysis of 254 glottis cancers: 87-T2a, 77-T2b and 90-T3 with anterior commissure (AC) involvement treated by OPHL at tertiary referral centre between 2001 and 2008. In 38/254 patients (15 %) PAF were found (16 prelaryngeal metastases, 22 other); more often in stage T2b/T3 versus T2a (p = 0.008). PAF other than prelaryngeal metastases were found more often in T2b than T2a tumours (p = 0.005). Outcomes revealed that out of 36 patients with local recurrence, 19 had PAF. Comparison of 216 patients with no PAF and 16 patients with prelaryngeal metastases revealed, respectively: 7.9 versus 81.3 % local recurrences (p = 0.034), 3.2 versus 68.8 % nodal recurrences (p = 0.011), 90.7 versus 43.8 % of 5-year organ preservation (p = 0.021) and 92.6 versus 75 % 5-year overall survival (p = 0.022). Out of 10 patients with close margins, 1 developed the local recurrence; impact ...Continue Reading

References

May 1, 1996·The Annals of Otology, Rhinology, and Laryngology·L RucciO Gallo
Feb 24, 2000·The Annals of Otology, Rhinology, and Laryngology·M S PerskyR O'Leary
Mar 29, 2001·The Journal of Laryngology and Otology·A A Maheshwar, C C Gaffney
Oct 16, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·W M MendenhallR W Hinerman
Feb 6, 2004·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Abderrahim ZouhairMahmut Ozsahin
Apr 28, 2004·Cancer·William M MendenhallDouglas B Villaret
Apr 5, 2005·The Laryngoscope·M M BarbosaS K Salviano
Dec 20, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Siarhei SpirydovichPaul Desrosiers
Feb 24, 2006·Archives of Otolaryngology--head & Neck Surgery·Elizabeth SigstonDaniel F Brasnu
Aug 16, 2006·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Patrick J BradleyAlfio Ferlito
Mar 23, 2007·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Marc RemacleJochen Werner
Oct 8, 2008·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Elisabeth Victoria SjögrenRobert Jan Baatenburg de Jong
May 16, 2009·Head & Neck Oncology·Sharad Chawla, Andrew Simon Carney
May 20, 2009·Archives of Otolaryngology--head & Neck Surgery·Edward D McCoul, Gady Har-El
Jul 15, 2009·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Carl E SilverAlfio Ferlito
Mar 5, 2011·Head & Neck·Konstantinos MantsopoulosHeinrich Iro
Sep 8, 2011·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Małgorzata WierzbickaAnna Bartochowska
Oct 13, 2011·Head & Neck·Dana M HartlGregory T Wolf
May 16, 2013·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·S Mark TaylorMatthew H Rigby
Jun 5, 2013·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·A Al-MamganiR J Baatenburg de Jong
Nov 10, 2013·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Nausheen JamalDinesh K Chhetri
Mar 7, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Aviram MizrachiJacob Shvero
Mar 29, 2014·Practical Radiation Oncology·W F MouradL B Harrison
Apr 3, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·G SuccoA R Antonelli
Aug 22, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Małgorzata LeszczyńskaWitold Szyfter

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