Adverse impact of mood on flow-mediated dilation.

Psychosomatic Medicine
Denise C CooperJoel E Dimsdale

Abstract

To examine the impact of mood states on endothelial function, as measured noninvasively by brachial artery flow-mediated dilation (FMD). Substantial literature indicates that negative mood is linked to cardiovascular disease (CVD). However, the mechanisms underlying this relationship are not well defined. CVD is often preceded by dysfunction of the endothelium. Healthy adults (n = 70; mean age, 36 years) completed the Profile of Mood States (POMS), which contains six subscales (depression/dejection; tension/anxiety; anger/hostility; confusion/bewilderment; fatigue/inertia; vigor/activity) that are used to compute a total mood disturbance score for overall psychological distress. FMD was calculated (maximum percentage change in brachial artery diameter) from ultrasound assessment of arterial diameter at baseline and for 10 minutes after occlusion. Regressions showed that increases in POMS total mood disturbance scores were associated with decreases in endothelial function. Mood disturbance explained 10% of the variance in FMD (p < .01), after controlling for age, sex, mean arterial pressure, body mass index, and socially desirable response bias. An exploratory set of separate regressions conducted to decompose the link between F...Continue Reading

References

Jun 1, 1983·Journal of Personality Assessment·S Shacham
Nov 1, 1995·Journal of the American College of Cardiology·T J AndersonA C Yeung
Apr 1, 1999·Journal of Clinical Psychology·D L NyenhuisA Parmentier
Jun 15, 1999·Psychosomatic Medicine·A SherwoodA L Hinderliter
Nov 15, 2000·Circulation·L GhiadoniJ E Deanfield
Jul 13, 2001·The American Journal of Cardiology·S RajagopalanB Pitt
Jan 15, 2002·Journal of the American College of Cardiology·Mary C CorrettiUNKNOWN International Brachial Artery Reactivity Task Force
Aug 7, 2002·Circulation·Joseph A Vita, John F Keaney
May 24, 2003·Psychosomatic Medicine·Kelly F HarrisLewis H Kuller
Aug 1, 1960·Journal of Consulting Psychology·D P CROWNE, D MARLOWE
Feb 13, 2004·Progress in Cardiovascular Diseases·Philip C Strike, Andrew Steptoe
Feb 2, 2006·Psychosomatic Medicine·Julie A WagnerGina Abbott
Feb 24, 2006·Journal of Psychiatric Research·Kosuke NaritaYuji Wada
Jul 4, 2006·Journal of the American College of Cardiology·Andrew J M BroadleyMichael P Frenneaux
Oct 19, 2006·International Journal of Cardiology·Lucia VenneriEugenio Picano
Jun 23, 2007·Current Pharmaceutical Design·Matthias Frick, Franz Weidinger
Jul 23, 2008·Perspectives in Vascular Surgery and Endovascular Therapy·Kimon Bekelis, Nicos Labropoulos
Jul 30, 2008·Endothelium : Journal of Endothelial Cell Research·Hasan Korkmaz, Orhan Onalan
Oct 3, 2008·Journal of Behavioral Medicine·Tin Kwang LinChin-Lon Lin
Mar 24, 2009·International Journal of Behavioral Medicine·Laura L SchottKim Sutton-Tyrrell

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Citations

Jan 20, 2011·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·K H LadwigM E Lacruz
Sep 29, 2011·Pflügers Archiv : European journal of physiology·Noboru Toda, Megumi Nakanishi-Toda
Oct 20, 2010·Clinical Rheumatology·Kyoung Im ChoTae Ik Kim
Oct 4, 2011·International Journal of Behavioral Medicine·Julie A WagnerNimrta Ghuman
Jun 19, 2013·Journal of Bodywork and Movement Therapies·Stacy D HunterHirofumi Tanaka
Apr 11, 2012·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Brent T MausbachIgor Grant
Apr 6, 2011·Cardiology in Review·Christopher M Celano, Jeff C Huffman
Jun 3, 2014·Journal of Women's Health·Liisa HantsooC Neill Epperson
Jun 28, 2015·Journal of Psychosomatic Research·Jess G FiedorowiczSrijan Sen
Feb 24, 2015·Journal of Neuroscience Research·Andrew A RebelColin K Combs
Jun 24, 2015·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Hui ShiGang Wang
May 9, 2013·Cardiovascular Psychiatry and Neurology·Jeff C HuffmanJames L Januzzi
Apr 30, 2013·Progress in Cardiovascular Diseases·Rebecca C ThurstonLaura D Kubzansky
Apr 8, 2011·Journal of Human Hypertension·L FitzGeraldD Shapiro
Jun 4, 2011·Psychosomatic Medicine·Denise C CooperJoel E Dimsdale
Jun 22, 2013·Psychosomatic Medicine·Ashley N StillmanWilliam G Haynes
Jan 15, 2014·International Journal of Rheumatic Diseases·Kyoung Im Cho, Ji Hyun Lee
Nov 17, 2020·Complementary Therapies in Medicine·Alexander A PiñaStacy D Hunter
Oct 28, 2020·International Journal of Molecular Sciences·Leonardo SandriniSilvia Stella Barbieri
Mar 15, 2020·Progress in Neuro-psychopharmacology & Biological Psychiatry·Marta Andrea SiragusaThomas Desmidt
Sep 14, 2021·Frontiers in Medicine·Enrico De LorenzisElisa Gremese

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