Adverse outcome after incident stroke hospitalization for Indigenous and non-Indigenous Australians in the Northern Territory

International Journal of Stroke : Official Journal of the International Stroke Society
Vincent HeJames N Burrow

Abstract

Survival after a stroke is lower for Indigenous than other stroke patients in Australia. It is not known whether recurrence is more common for Indigenous patients, or whether their higher prevalence of comorbidity affects their lower survival. This study aimed to investigate the stroke recurrence and role of comorbidities in adverse stroke outcomes (recurrence and death) for Indigenous compared with other Australians. A retrospective cohort study of first hospitalization for stroke (n = 2105) recorded in Northern Territory hospital inpatient data between 1996 and 2011 was conducted. For the multivariable analyses of adverse outcomes, logistic regression was used for case fatality and competing risk analysis for recurrent stroke and long-term death. Comorbidities (identified from inpatient diagnosis data) were analyzed using the Charlson Comorbidity Index (modified for stroke outcomes). Prevalence of comorbidities, case fatality, incidence of re-hospitalization for recurrent stroke, and long-term death rate were higher for Indigenous than non-Indigenous stroke patients. Adjustment for comorbidity in multivariable analyses considerably reduced Indigenous patients' excess risk for case fatality (odds ratio: 1·25, 0·88-1·78) and lo...Continue Reading

References

Sep 8, 2000·Stroke; a Journal of Cerebral Circulation·G J HankeyE G Stewart-Wynne
Sep 8, 2001·Stroke; a Journal of Cerebral Circulation·H Brønnum-HansenUNKNOWN Danish MONICA Study Group
Jul 3, 2004·Stroke; a Journal of Cerebral Circulation·Larry B GoldsteinRonnie D Horner
Sep 7, 2004·The Medical Journal of Australia·Andy H LeeKelvin K W Yau
May 10, 2005·Stroke; a Journal of Cerebral Circulation·Devin L BrownLewis B Morgenstern
Feb 24, 2006·The Medical Journal of Australia·Elizabeth May PepperTarun S Weeramanthri
Oct 13, 2006·Statistics in Medicine·H PutterR B Geskus
Nov 23, 2006·Nature Clinical Practice. Neurology·Pierre Fayad
Aug 19, 2008·International Journal of Stroke : Official Journal of the International Stroke Society·Amanda G Thrift, Noel Hayman
Jun 6, 2009·American Journal of Epidemiology·Bryan LauStephen J Gange
Sep 29, 2009·European Journal of Internal Medicine·Luis Castilla-GuerraJesus Alvarez-Suero
Apr 16, 2011·Stroke; a Journal of Cerebral Circulation·Judith M KatzenellenbogenJames P Codde
Feb 4, 2012·International Journal of Stroke : Official Journal of the International Stroke Society·Monique F KilkennyUNKNOWN National Stroke Foundation
Apr 15, 2014·International Journal of Stroke : Official Journal of the International Stroke Society·Judith M KatzenellenbogenSandra C Thompson
Jan 16, 2015·International Journal of Stroke : Official Journal of the International Stroke Society·Jiqiong YouSteven L Guthridge
Feb 24, 2015·Australian Health Review : a Publication of the Australian Hospital Association·Yuejen ZhaoVincent He

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Citations

Feb 16, 2017·Practical Neurology·Prashanth Ramachandran
Apr 1, 2019·Acta Neurologica Scandinavica·Andrej Netland KhanevskiUNKNOWN NOR-STROKE study group
Feb 20, 2019·Australian Health Review : a Publication of the Australian Hospital Association·Clementine LabroscianoIsuru Ranasinghe
Jul 29, 2021·Scientific Reports·Ting-Ann WangSherry Yueh-Hsia Chiu

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