Adverse pregnancy outcomes associated with moderate elevations in blood pressure or blood glucose in Ugandan women; a prospective cohort study.

AJOG Global Reports
Jack MillnMoffat J Nyirenda

Abstract

The association between overt hypertension and diabetes and adverse pregnancy outcomes is well documented. Recent evidence suggests that even moderate elevations in blood pressure or blood glucose may confer a significant risk in a dose-dependent manner. However, these studies have primarily been undertaken in white populations in high-income settings. Hypertension and diabetes are emerging as major public health issues in sub-Saharan Africa as the region undergoes rapid urbanization. It is therefore important to understand how such noncommunicable conditions contribute to pregnancy outcomes in these populations. This study aimed to determine the association between stage 1 hypertension or fasting blood glucose in the gestational diabetes mellitus-range and adverse pregnancy outcomes in Uganda, and to describe the effects of other contributing factors such as maternal obesity. This was a prospective cohort study of 2857 women at 5 major hospitals in urban and semiurban central Uganda. Women were enrolled at 24 to 28 weeks' gestation. Data about the maternal demographics, anthropometrics, fasting venous blood glucose, blood pressure, and pregnancy outcomes were collected. Moderate elevations in blood pressure and blood glucose w...Continue Reading

References

Apr 12, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·T FarrellT Cundy
Feb 12, 2004·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·B C OzumbaJ M Oli
Jun 14, 2005·The New England Journal of Medicine·Caroline A CrowtherUNKNOWN Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group
May 9, 2008·The New England Journal of Medicine·UNKNOWN HAPO Study Cooperative Research GroupDavid A Sacks
Nov 20, 2008·Archives of Gynecology and Obstetrics·C I KamanuM Obasi
Oct 3, 2009·The New England Journal of Medicine·Mark B LandonUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
Jan 22, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·UNKNOWN HAPO Study Cooperative Research Group
Mar 2, 2010·Diabetes Care·UNKNOWN International Association of Diabetes and Pregnancy Study Groups Consensus PanelMaria Ines Schmidt
Jun 1, 2010·American Journal of Obstetrics and Gynecology·Donald R CoustanUNKNOWN International Association of Diabetes and Pregnancy Study Groups
Mar 13, 2014·BMJ : British Medical Journal·Tim CundyEdmond A Ryan
Apr 17, 2014·BMJ : British Medical Journal·Kate BramhamLucy C Chappell
Jun 4, 2014·PloS One·Shelley MacaulayShane A Norris
Aug 18, 2016·Best Practice & Research. Clinical Obstetrics & Gynaecology·Peter von Dadelszen, Laura A Magee
Sep 12, 2018·Obstetrics and Gynecology·Elizabeth F SuttonJanet M Catov
Dec 24, 2018·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists' Committee on Practice Bulletins—Obstetrics
Jul 1, 2019·American Journal of Obstetrics and Gynecology·Alisse HauspurgHyagriv Simhan
Jul 17, 2019·BMJ : British Medical Journal·Graham J BurtonAshley Moffett
Dec 20, 2019·Obstetrics and Gynecology·UNKNOWN Committee on Practice Bulletins—Obstetrics
Jan 20, 2020·American Journal of Obstetrics and Gynecology·Maya ReddyKirsten Palmer
Jun 17, 2020·Obstetrics and Gynecology·Elizabeth F SuttonJanet M Catov
Nov 7, 2020·American Journal of Obstetrics and Gynecology·Victoria R GreenbergHeather S Lipkind

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