PMID: 3320735Sep 1, 1987Paper

Adverse reactions associated with parenteral beta agonists: serum potassium changes

New England and Regional Allergy Proceedings
S L Spector

Abstract

Beta adrenergic agonists can lower serum potassium levels predominantly when they are administered by the parenteral route. Hypokalemia has been demonstrated with the use of albuterol given by the intramuscular, intravenous and subcutaneous (SC) routes as well as with SC epinephrine. The effect appears to be dose related. Certain patients might be at increased risk who are on medications that tend to lower potassium such as corticosteroids, theophylline, diuretics or digoxin. Further studies should be encouraged on the hypokalemic effect of all forms of beta agonists in view of their possible contribution toward arrhythmias and asthma deaths.

Citations

Apr 23, 2008·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Joel S KleinMichael Rich
Jun 1, 1992·Journal of Clinical Pharmacy and Therapeutics·C A Haffner, M J Kendall

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