Adverse reactions following administration of contrast media for diagnostic imaging in anaesthetized dogs and cats: a retrospective study

Veterinary Anaesthesia and Analgesia
Stefania ScarabelliBriony Alderson

Abstract

To evaluate incidences of adverse reaction after the administration of contrast media. Retrospective observational study. Animals included 356 dogs and 58 cats receiving non-ionic iodinated contrast agents, and 425 dogs and 49 cats receiving gadolinium-based contrast agents. Anaesthesia records of dogs and cats receiving intravenous (IV) gadobutrol for magnetic resonance imaging (MRI) or IV iohexol for computed tomography (CT) were reviewed. Changes in pulse rate, respiratory rate and mean arterial pressure at 5 minutes after administration of the contrast medium were evaluated. Changes of 10-20% were considered mild, those of >20% moderate, and reactions that required immediate treatment were considered severe. Associations of sex, age and weight with contrast reaction were investigated using logistic regression. Differences in the incidences of reactions to CT and MRI contrast media were examined with chi-squared tests. A p-value of <0.05 was considered to indicate statistical significance. Of cats receiving iohexol, eight (13.8%) had mild and 10 (17.2%) had moderate reactions. Of cats receiving gadobutrol, six (12.2%) had mild and six (12.2%) had moderate reactions. No cats had severe reactions and the risk for reaction was ...Continue Reading

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Citations

Feb 11, 2020·Frontiers in Veterinary Science·J Scott McNallyRonald W Day
Sep 7, 2017·The British Journal of Radiology·Ingrid BoehmJohannes Thomas Heverhagen
Sep 24, 2020·The Journal of Veterinary Medical Science·Haruka TamogiKazuto Yamashita
Jun 15, 2021·Journal of the American Veterinary Medical Association·Julianne E McCreadyHugues Beaufrěre
Feb 22, 2017·Veterinary Anaesthesia and Analgesia·Chiara Adami, Karine Gendron

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